In starfish oocytes, activity of the maturation-promoting factor (MPF) and that of a major
cAMP-independent protein kinase dropped at the time of meiotic cleavage, and rose again …

cAMP receptor proteins present in mammalian brain were identified and characterized with
the use of the photoaffinity label 8-azido [32P] cAMP. Cytosol and membrane fractions from …

A significant number of proteins in both eukaryotes and prokaryotes are known to be post-
translationally modified by the addition of phosphate, serving as a means of rapidly …

Thyrotropin-releasing hormone (TRH) is a tripeptide that rapidly enhances prolactin
secretion in clonal, hormone-responsive GH3 rat pituitary cells. In an effort to identify …

The catalytic subunit of cAMP-dependent protein kinase contains two stable phosphorylation
sites, Thr-197 and Ser-338 (Shoji, S., Titani, K., Demaille, JG, and Fischer, EH (1979) J. Biol …

A series of perylenequinonoid pigments (PQPs) and related compounds were synthesized
and screened for the inhibition of protein kinase C (PKC), a key enzyme involved in cellular …

The addition of the tumor promoting phorbol ester 12-O-tetradecanoyl phorbol 13-acetate to
intact human red blood cells activates protein kinase C and stimulates the phosphorylation …

Effect of phosphomimicking mutations of 14-3-3ζ on its interaction with phosphorylated
shortest isoform of human tau protein and phosphorylated human small heat shock protein …

The structural and chemical specificity of diacylglycerols, lipid components of the quaternary
complex for protein kinase C activation, have been evaluated. The ether-linked analogs of …

The functional activity of Cdc42 is known to be regulated by proteins that control its
GDP/GTP-bound state. However, there is still limited information on how Cdc42 is controlled …