New functions and potential applications of amino acids

H Uneyama, H Kobayashi, N Tonouchi - Amino Acid Fermentation, 2017 - Springer
Currently, several types of amino acids are being produced and used worldwide.
Nevertheless, several new functions of amino acids have been recently discovered that …

Targeting mGlu5 for methamphetamine use disorder

J Petzold, KK Szumlinski, ED London - Pharmacology & therapeutics, 2021 - Elsevier
Methamphetamine abuse leads to devastating consequences, including addiction, crime,
and death. Despite decades of research, no medication has been approved by the US Food …

Association of Glutamate Infusion With Risk of Acute Kidney Injury After Coronary Artery Bypass Surgery: A Pooled Analysis of 2 Randomized Clinical Trials

J Holm, F Vanky, R Svedjeholm - JAMA Network Open, 2024 - jamanetwork.com
Importance Acute kidney injury (AKI) after cardiac surgery is associated with increased
morbidity and mortality, and measures to prevent AKI have had limited success. Glutamate …

Chronic widespread pain: increased glutamate and lactate concentrations in the trapezius muscle and plasma

B Gerdle, B Larsson, F Forsberg… - The Clinical journal …, 2014 - journals.lww.com
Background: Chronic widespread pain (CWP), including fibromyalgia syndrome (FM), is
associated with prominent negative consequences. CWP has been associated with …

EuroSCORE II and N-terminal pro-B-type natriuretic peptide for risk evaluation: an observational longitudinal study in patients undergoing coronary artery bypass graft …

J Holm, M Vidlund, F Vánky, Ö Friberg… - British journal of …, 2014 - academic.oup.com
Background Postoperative heart failure remains the major cause of death after cardiac
surgery. As N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a predictor for …

[HTML][HTML] Glutamate Infusion Reduces Myocardial Dysfunction after Coronary Artery Bypass Grafting According to NT-proBNP: Summary of 2 Randomized Controlled …

J Holm, F Vanky, R Svedjeholm - The American Journal of Clinical Nutrition, 2023 - Elsevier
Background Glutamate is reported to enhance the recovery of oxidative metabolism and
contractile function of the heart after ischemia. The effect appears to be blunted in diabetic …

Rise and fall of NT-proBNP in aortic valve intervention

H Hultkvist, J Holm, R Svedjeholm, F Vánky - Open heart, 2018 - openheart.bmj.com
Objectives To describe the dynamics of N-terminal pro-B-type natriuretic peptide (NT-
proBNP) from preoperative evaluation to 6-month follow-up in patients undergoing aortic …

Glutamate infusion associated with reduced rises of p‐Copeptin after coronary surgery: Substudy of GLUTAMICS II

R Svedjeholm, G Ferrari, F Vanky… - Acta …, 2023 - Wiley Online Library
Background Glutamate plays a key role for post‐ischaemic recovery of myocardial
metabolism. According to post hoc analyses of the two GLUTAMICS trials, patients without …

[HTML][HTML] Effect of glutamate infusion on NT-proBNP after coronary artery bypass grafting in high-risk patients (GLUTAMICS II): A randomized controlled trial

J Holm, G Ferrari, A Holmgren, F Vanky, Ö Friberg… - PLoS …, 2022 - journals.plos.org
Background Animal and human data suggest that glutamate can enhance recovery of
myocardial metabolism and function after ischemia. N-terminal pro-brain natriuretic peptide …

[HTML][HTML] Evaluation of left ventricular diastolic function in patients operated for aortic stenosis

H Hultkvist, E Nylander, É Tamás, R Svedjeholm… - Plos one, 2022 - journals.plos.org
Background Left ventricular diastolic dysfunction is common in patients with aortic valve
stenosis (AS) and reportedly affects prognosis after surgical aortic valve replacement …