Clinical applications of near-infrared diffuse correlation spectroscopy and tomography for tissue blood flow monitoring and imaging

Y Shang, T Li, G Yu - Physiological measurement, 2017 - iopscience.iop.org
Objective. Blood flow is one such available observable promoting a wealth of physiological
insight both individually and in combination with other metrics. Approach. Near-infrared …

NIR spectroscopic detection of breast cancer

S Nioka, B Chance - Technology in cancer research & …, 2005 - journals.sagepub.com
Near infrared spectroscopy (NIRS) utilizes intrinsic optical absorption signals of blood,
water, and lipid concentration available in the NIR window (600–1000 nm) as well as a …

Three-dimensional in vivo fluorescence diffuse optical tomography of breast cancer in humans

A Corlu, R Choe, T Durduran, MA Rosen… - Optics express, 2007 - opg.optica.org
We present three-dimensional (3D) in vivo images of human breast cancer based on
fluorescence diffuse optical tomography (FDOT). To our knowledge, this work represents the …

Time-domain diffuse correlation spectroscopy (TD-DCS) for noninvasive, depth-dependent blood flow quantification in human tissue in vivo

S Samaei, P Sawosz, M Kacprzak, Ż Pastuszak… - Scientific reports, 2021 - nature.com
Monitoring of human tissue hemodynamics is invaluable in clinics as the proper blood flow
regulates cellular-level metabolism. Time-domain diffuse correlation spectroscopy (TD-DCS) …

Influences of tissue absorption and scattering on diffuse correlation spectroscopy blood flow measurements

D Irwin, L Dong, Y Shang, R Cheng… - Biomedical optics …, 2011 - opg.optica.org
In this study we evaluate the influences of optical property assumptions on near-infrared
diffuse correlation spectroscopy (DCS) flow index measurements. The optical properties …

Real‐time In Situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light

G Yu, T Durduran, C Zhou, TC Zhu… - Photochemistry and …, 2006 - Wiley Online Library
Photodynamic therapy (PDT) requires oxygen to cause cellular and vascular tumor damage.
Tissue oxygen concentration, in turn, is influenced by blood flow and blood oxygenation …

Diffuse correlation spectroscopy with a fast Fourier transform-based software autocorrelator

J Dong, R Bi, JH Ho, PSP Thong… - Journal of biomedical …, 2012 - spiedigitallibrary.org
Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that probes
the deep tissue blood flow, by using the time-averaged intensity autocorrelation function of …

Hand-held based near-infrared optical imaging devices: a review

SJ Erickson, A Godavarty - Medical engineering & physics, 2009 - Elsevier
Near-infrared (NIR) optical imaging is a non-invasive and non-ionizing modality that is
emerging as a diagnostic/prognostic tool for breast cancer and other applications related to …

Imaging complex structures with diffuse light

SD Konecky, GY Panasyuk, K Lee, V Markel… - Optics express, 2008 - opg.optica.org
We use diffuse optical tomography to quantitatively reconstruct images of complex phantoms
with millimeter sized features located centimeters deep within a highly-scattering medium. A …

High-density diffuse correlation tomography with enhanced depth localization and minimal surface artefacts

R Paul, K Murali, HM Varma - Biomedical optics express, 2022 - opg.optica.org
A spatially weighted filter applied to both the measurement and the Jacobian is proposed for
high-density diffuse correlation tomography (DCT) to remove unwanted extracerebral …