Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) remain common
complications of sepsis. Unfortunately, development of effective pharmacologic and …

Sepsis remains to be a significant health care issue associated with high mortality and
healthcare cost, despite the extensive effort to better understand the pathophysiology of the …

Background Administration of certain general anesthetics to rodents during the
synaptogenic phase of neurodevelopment produces neuronal injury. Preconditioning …

Background: Isoflurane may be protective in preclinical models of lung injury, but its use in
patients with lung injury remains controversial and the mechanism of its protective effects …

Background Sevoflurane is one of the most commonly used volatile anesthetic agents with
the fastest onset and offset, replacing isoflurane in modern anesthesiology. Preconditioning …

Gram-negative bacteria remain the leading cause of sepsis, a disease that is consistently in
the top 10 causes of death internationally. Curing bacteremia alone does not necessarily …

Objective The aim of this meta-analysis is to compare the potential effects of inhalation
anesthetics with total intravenous anesthetics on alveolar cytokine expression and lung …

BACKGROUND: Mechanical ventilation leads to ventilator-induced lung injury in animals,
and can contribute to acute lung injury/acute respiratory distress syndrome in humans. Acute …

Volatile anesthetic isoflurane (ISO) has immunomodulatory effects. The fungal component
zymosan (ZY) induces inflammation through toll‐like receptor 2 or dectin‐1 signaling. We …

Patients with stroke have a high risk of infection which may be predicted by age,
procalcitonin, interleukin-6, C-reactive protein, National Institute of Health stroke scale …