Importance Polygenic risk scores (PRS) are predictors of the genetic susceptibility to
diseases, calculated for individuals as weighted counts of thousands of risk variants in which …

Suicidal thoughts and behaviors (STBs) are major public health problems that have not
declined appreciably in several decades. One of the first steps to improving the prevention …

Antipsychotic drugs are central to the treatment of schizophrenia and other psychotic
disorders but are ineffective for some patients and associated with side-effects and …

The long‐term benefit‐to‐risk ratio of sustained antipsychotic treatment for schizophrenia
has recently been questioned. In this paper, we critically examine the literature on the long …

Nonadherence with medication occurs in all chronic medical disorders. It is a particular
challenge in schizophrenia due to the illness's association with social isolation, stigma, and …

Background Antipsychotic medication reduces the severity of serious mental illness (SMI)
and improves patient outcomes only when medicines were taken as prescribed …

Antipsychotics are the drugs prescribed to treat psychotic disorders; however, patients often
fail to adhere to their treatment, and this has a severe negative effect on prognosis in these …

METHODS A group of 8 experts on the management of schizophrenia and LAIs met to
evaluate the evidence and to develop a set of recommendations regarding the clinical use …

Background: Nonadherence to medication is a recognized problem and may be the most
challenging aspect of treatment. Methods: We performed a systematic review of factors that …

Adherence to antipsychotics improves outcome in schizophrenia. There is a lack of
consensus on which factors most influence adherence behaviour and methodological …