Functional somatic syndromes (FSS), like irritable bowel syndrome or fibromyalgia and other
symptoms reflecting bodily distress, are common in practically all areas of medicine …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …

Central sensitization (CS), simply defined as an amplified response of the central nervous
system to peripheral input, is a concept of great importance in clinical medicine. It has …

Skeletal muscle exhibits great plasticity in response to altered activity levels, ultimately
resulting in tissue remodelling and substantial changes in mass. Animal research would …

Background Many patients consult their GP because they experience bodily symptoms. In a
substantial proportion of cases, the clinical picture does not meet the existing diagnostic …

Objective To study the prevalence and clinical characteristics of Somatic Symptom Disorder
(SSD), Bodily Distress Syndrome (BDS) and fibromyalgia syndrome (FMS) and their overlap …

Prevalence of functional somatic syndromes (FSS) in the general population varies with
observed overlap between syndromes. However, studies including a range of FSS are …

Objective The harmonization of core outcome domains in clinical trials facilitates comparison
and pooling of data, and simplifies the preparation and review of research projects and …

Background Conceptualisation and classification of functional disorders appear highly
inconsistent in the health-care system, particularly in primary care. Numerous terms and …

Background People with multiple and persistent physical symptoms have impaired quality of
life and poor experiences of health care. We aimed to evaluate the effectiveness of a …