Pathogenic cellular and molecular mediators in lupus nephritis

C Mohan, T Zhang, C Putterman - Nature Reviews Nephrology, 2023 - nature.com
Kidney involvement in patients with systemic lupus erythematosus—lupus nephritis (LN)—is
one of the most important and common clinical manifestations of this disease and occurs in …

Potential small molecules for therapy of lupus nephritis based on genetic effect and immune infiltration

J Qing, W Song, L Tian, SB Samuel… - BioMed Research …, 2022 - Wiley Online Library
Lupus nephritis (LN) is the most common and significant complication of systemic lupus
erythematosus (SLE) due to its poor prognosis and mortality rates in SLE patients. There is a …

Urinary biomarkers for lupus nephritis: a systems biology approach

MH Omer, A Shafqat, O Ahmad, J Nadri… - Journal of Clinical …, 2024 - mdpi.com
Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disorder.
Kidney involvement, termed lupus nephritis (LN), is seen in 40–60% of patients with …

Discovery of novel circulating immune complexes in lupus nephritis using immunoproteomics

C Tang, M Fang, G Tan, S Zhang, B Yang, Y Li… - Frontiers in …, 2022 - frontiersin.org
Objective The goal is to discover novel circulating immune complexes (ICx) in the serum of
lupus nephritis (LN) as potential biomarkers. Methods Protein A/G magnetic beads or C1q …

Urine soluble CD163 is a promising biomarker for the diagnosis and evaluation of lupus nephritis

YJ Huang, CH Lin, HY Yang, SF Luo… - Frontiers in …, 2022 - frontiersin.org
Introduction Urine-soluble CD163 (usCD163) is released from alternatively activated
macrophages involved in the resolution of inflammation in glomeruli and plays an important …

Potential biomarkers for active renal involvement in systemic lupus erythematosus patients

L Xiao, W Xiao, S Lin - Frontiers in Medicine, 2022 - frontiersin.org
Objective This study aimed to identify the key genes related to active renal involvement in
patients with systemic lupus erythematosus (SLE). Methods Microarray datasets were …

Búsqueda de biomarcadores de daño renal en pacientes con lupus eritematoso sistémico a través un abordaje metabolómico no dirigido

A Rojo Sánchez - 2023 - bonga.unisimon.edu.co
El lupus eritematoso sistémico (LES) es la enfermedad autoinmune multiorgánica
prototípica, que se relaciona con una alta morbilidad y muerte temprana de personas en …

Glomerulopatia colapsante idiopática: bases moleculares e correlações entre parâmetros moleculares, proteômicos, clínicos e histológicos

PDMM Neves - 2023 - teses.usp.br
A glomerulopatia colapsante (GC) é uma doença glomerular grave, que se apresenta
frequentemente como síndrome nefrótica com proteinúria maciça e rápida evolução para …

Aberrant expression of C1q, IL-6 and β-catenin in class VI lupus nephritis

J Xue, Y Min, Z Zhu, Y Jia, S Chi, J Chen - 2023 - researchsquare.com
Background: complement component C1q, interleukin-6 (IL-6) and β-catenin have been
implicated in the pathogenesis of lupus nephritis (LN). However, their correlation with the …

Urine CD163 is a Promising Biomarker for the Diagnosis and Evaluation of Lupus Nephritis

YJ Huang, CH Lin, Y Huang-Yu, SF Luo, CF Kuo - 2022 - researchsquare.com
Objectives Urine soluble CD163 (usCD163) is released from alternatively activated
macrophages involved in the resolution of inflammation in glomeruli, and plays an important …