Alcohol use and metabolic syndrome are highly prevalent in the population and frequently
co-exist. Both are implicated in a large range of health problems, including chronic liver …

Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …

Simple Summary A large number of studies report that medicinal herbs and many food
ingredients protect against the development of liver disease because they possess …

During aging, body adiposity increases with changes in the metabolism of lipids and their
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …

Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …

Chronic liver diseases are a major cause of morbidity and mortality worldwide. Recently, gut
dysbiosis was identified as an important factor in the pathogenesis of liver diseases. The …

Heavy alcohol use is the cause of alcoholic liver disease (ALD). The ALD spectrum ranges
from alcoholic steatosis to steatohepatitis, fibrosis, and cirrhosis. In Western countries …

Background & Aims Individual risk for developing alcohol-related liver disease (ALD) varies
greatly. We hypothesized that metabolic risk factors and genetic polymorphisms predict …

Objective To summarize the structure, regulatory mechanism, and target genes of hypoxia-
inducible factor-1 alpha (HIF-1α) and to comprehensively expound its role in various chronic …