Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

Over the past 25 years, successive cloning of SLC34A1, SLC34A2 and SLC34A3, which
encode the sodium-dependent inorganic phosphate (Pi) cotransport proteins 2a–2c, has …

Phosphorus, an essential nutrient, performs vital functions in skeletal and non-skeletal
tissues and is pivotal for energy production. The last two decades of research on the …

Concentrations of selenium that exceed regulatory guidelines have been associated with
coal mining activities and have been linked to detrimental effects on aquatic ecosystems and …

Introduction: The management of hyperphosphatemia in patients with chronic kidney
disease (CKD) is complicated, requiring a multidisciplinary approach that includes dietary …

Nicotinamide is an important regulator of Pi homeostasis after conversion into NAD+/NADH.
In this work, we have studied the classical inhibition of Pi transport by these compounds in …

We have studied inorganic phosphate (Pi) handling in rat aortic vascular smooth muscle
cells (VSMC) using 32P-radiotracer assays. Our results have revealed a complex set of …

Abstract Fibroblast growth factor 23 (FGF23) is a circulating hormone derived from the bone
whose release is controlled by many factors and exerts a multitude of systemic actions …

We have studied the role of the intestine, kidney, and several hormones when adapting to
changes in dietary P concentration. Normal and parathyroidectomized (PTX) rats were fed …

Inorganic phosphate (Pi) is a constituent of important biological molecules (eg, nucleic acids
and phospholipids) and is essential for cellular energetics and signaling, and protein …