Endovascular thrombectomy for anterior circulation large vessel occlusion stroke: an evolution of trials

N Starikova, S Räty, D Strbian, DPO Kaiser… - Seminars in …, 2023 - thieme-connect.com
The last decade's progress in demonstrating the clinical benefit of endovascular
thrombectomy (EVT) in patients with large vessel occlusion stroke has transformed the …

Endovascular therapy for acute stroke: new evidence and indications

A Sahoo, M Abdalkader, H Yamagami… - Journal of …, 2023 - jstage.jst.go.jp
Endovascular therapy (EVT) has revolutionized the treatment of acute ischemic stroke. In the
past few years, endovascular treatment indications have expanded to include patients being …

Basilar artery occlusion thrombectomy technique: an international survey of practice patterns

P Klein, A Herning, B Drumm, J Raymond… - Stroke: Vascular and …, 2023 - Am Heart Assoc
Background Two recent trials demonstrated a benefit for endovascular therapy (EVT) in the
treatment of basilar artery occlusion (BAO). In light of the expected increase in the use of …

Stroke genetics and how it Informs novel drug discovery

J Valančienė, K Melaika, A Šliachtenko… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Stroke is one of the main causes of death and disability worldwide.
Nevertheless, despite the global burden of this disease, our understanding is limited and …

Defining light transmission aggregometry cutoff values for clopidogrel and aspirin resistance in flow diversion treatment of intracranial aneurysms

A Enriquez-Marulanda, J Filo… - Journal of …, 2024 - thejns.org
OBJECTIVE Concern about thromboembolic events after flow diversion (FD) warrants dual
antiplatelet therapy for 3 to 6 months. Platelet function tests are routinely performed prior to …

[HTML][HTML] Molecular genomic and epigenomic characteristics related to aspirin and clopidogrel resistance

J Kim, BS Shin, DH Kim, DI Shin, SH Ahn, JG Kim… - BMC Medical …, 2024 - Springer
Background Mediators, genomic and epigenomic characteristics involving in metabolism of
arachidonic acid by cyclooxygenase (COX) and lipoxygenase (ALOX) and hepatic activation …

Genotype-guided dual antiplatelet therapy in cerebrovascular disease: assessing the risk and benefits for ethnic populations

K Qureshi, MU Farooq, PB Gorelick - Expert review of …, 2023 - Taylor & Francis
Introduction Cerebrovascular disease is a leading cause of morbidity and mortality in the
world and antiplatelet therapy is a main pharmacologic means of secondary prevention …

Anticoagulants Antiplatelets and Antifibrinolytics

JR Seshan - Principles and Practice of Neurocritical Care, 2024 - Springer
Coagulopathy refers to an abnormal state of hemostasis. The incidence of coagulopathy in
neurocritical care is described variedly between 14 and 80% and affects the prognosis of …

Safety of dual antiplatelet therapy using aspirin and low-dose Prasugrel with platelet reactivity testing in flow diverter treatment of intracranial aneurysms

LM Flynn, E Mohamed, N Dobbs… - Interventional …, 2023 - journals.sagepub.com
Background Dual antiplatelet therapy (DAPT) is standard care for intracranial stenting to
prevent thrombotic complications. Clopidogrel resistance has resulted in patients receiving …

Cost-Effectiveness of Platelet Function Testing in Dual Antiplatelet Therapy After Intracranial Aneurysm Flow Diversion

A Wadhwa, F Ramirez-Velandia, EO Mensah, M Salih… - medRxiv, 2024 - medrxiv.org
Introduction: Dual antiplatelet therapy (DAPT) use is the standard of practice after flow
diversion (FD) for intracranial aneurysms (IAs). Yet, no consensus exists in the literature …