Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Abstract Treatment of migraine is on the cusp of a new era with the development of drugs
that target the trigeminal sensory neuropeptide calcitonin gene-related peptide (CGRP) or its …

Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …

Classical migraine patients experience aura, which is transient neurological deficits
associated with cortical spreading depression (CSD), preceding headache attacks. It is not …

Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …

Several lines of evidence pointed to an important role for CGRP in migraine. These included
the anatomic colocalization of CGRP and its receptor in sensory fibers innervating pain …

Objective We aimed (1) to analyze salivary calcitonin gene‐related peptide (CGRP) levels in
patients with migraine,(2) to predict erenumab response from baseline CGRP levels, and (3) …

Ethnopharmacological relevance Migraines have become a major threat to human health,
as they significantly affect human health and quality of life due to a high prevalence rate …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

Chronic migraine is one of the most devastating headache disorders. The estimated
prevalence is 1.4–2.2% in the population. The factors which may predispose to the process …