The novel histone deacetylase drug chidamide (CHI) has been proven to regulate gene
expression associated with oncogenesis via epigenetic mechanisms. However, huge side …

Most of the conventional dosage forms are associated with severe adverse effects and do
not produce satisfactory therapeutic response due to nonspecificity, uncontrolled release …

In this paper, the dimer of pyropheophorbide a via 3 1-ether bond linkage as novel chlorin
photosensitizers (PSs) for tumor photodynamic therapy (PDT) was designed and …

Epigenetics is a set of mechanisms for regulating gene transcription involved in
physiological and pathological processes including cancer. Histone acetylation, regulated …

西达本胺是我国自主研发合成的首个亚型选择性组蛋白脱乙酰化酶抑制剂(HDACi),
属于表观遗传学相关药物. 组蛋白是人体内染色体的基本组成单位之一, 其乙酰化作用在肿瘤的 …

Cancer remains a major health issue in NZ and worldwide. Conventional treatments such as
surgery, radiation and chemotherapy have limited ability to treat cancers and cause …

One of the deadliest forms of malignancy affecting females worldwide alongside breast
cancer is cervical cancer, which urgently calls for novel treatment approaches. Gold …

The development of multifunctional nanoparticles has greatly expanded the application of
nanomedicines for various health care ailments with better diagnosis and therapy. The …

The development of theranostic nanoparticles has greatly expanded the application of
nanomedicines for different types of cancers with better diagnosis and therapy. The …

RESUMO REIS, Sara Rhaissa Rezende dos. Desenvolvimento de sistema troiano de
entrega de fármacos: nanopartículas biencapsuladas com dacarbazina e ftalocianina de …