The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats

G Ibrahim Fouad, M R. Mousa - Molecular and Cellular Biochemistry, 2021 - Springer
Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac
tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and …

Toxins mechanism in instigating hepatotoxicity

S Nithiyanandam, S Evan Prince - Toxin Reviews, 2021 - Taylor & Francis
Myriad of therapeutic drugs used in clinical practice have led to hepatotoxicity reporting
more than 1,100 pharmaceutical and chemical products with liver injury. Drug-induced liver …

Comparative study between effects of ginkgo biloba extract and extract loaded on gold nanoparticles on hepatotoxicity induced by potassium bromate

AS Osman, SE Abu-Risha, SM Bakr, AE Altyar… - … Science and Pollution …, 2023 - Springer
In human organs, potassium bromate (KBrO3) produces toxicity. The main causes of KBrO3
hepatotoxicity are the formation of reactive oxygen species (ROS) and DNA damage. The …

In vivo protective effects of Ginkgo biloba L. leaf extract against hydrogen peroxide toxicity: cytogenetic and biochemical evaluation

E Yalçın, K Çavuşoğlu, A Acar, K Yapar - Environmental Science and …, 2020 - Springer
In this study, the protective effects of Ginkgo biloba leaf extract (GbE) against toxicity induced
by hydrogen peroxide (H 2 O 2) in Swiss albino mice were investigated. Abnormal …

[HTML][HTML] Impact of gervital against histopathological, ultrastructural, and biochemical alterations caused by methotrexate or azathioprine in albino rat testis

M Abdul-Hamid, ES Abdel-Reheim, W Hegazy… - … Science and Pollution …, 2023 - Springer
Methotrexate (MTX) and azathioprine (AZA) are chemotherapeutic, immunosuppressive,
cytotoxic drugs with reported adverse effects, including oxidative damage to testis. This …

[HTML][HTML] Protective role of ferulic acid and/or gallic acid against pulmonary toxicity induced by amiodarone in rats

R Alazragi - Archives of Pharmacy Practice, 2020 - archivepp.com
Amiodarone is an orally active antiarrhythmic drug generally used throughout the world,
causing pulmonary toxicity as one of its most harmful side effects. The efficacy of two …

Beta vulgaris L. var cicla decreases liver injury induced by antiarrhytmic agent, Amiodarone

IB Turkyilmaz, S Sancar, S Bolkent… - Chemistry & …, 2024 - Wiley Online Library
Amiodarone (AMD) is an effective antiarrhythmic drug, but its long‐term usage strongly
forms liver toxicity due to its accumulation tendency. The chard is a unique plant which has a …

Appraisal of amiodarone-loaded PLGA nanoparticles for prospective safety and toxicity in a rat model

A Motawea, DAM Ahmed, AS Eladl, AAER El-Mansy… - Life Sciences, 2021 - Elsevier
Aims Amiodarone (AM) is a highly efficient drug for arrhythmias treatment, but its extra-
cardiac adverse effects offset its therapeutic efficacy. Nanoparticles (NPs)-based delivery …

Effect of Rythmol (propafenone HCl) administration during pregnancy in Wistar rats

ER Abd‐Allah, S Amin… - … of Biochemical and …, 2022 - Wiley Online Library
Propafenone is a well‐known Class 1C antiarrhythmic agent that has sodium channel
blocking properties as well as the ability to block 13 other channels and a modest calcium …

Successful Management of Severe Manganese Toxicosis in Two Dogs

J Wolf, L Hoffman, C Southern - Journal of the American …, 2023 - meridian.allenpress.com
Manganese is a common component of human joint supplements and may be a source of
ingestion and subsequent toxicosis in dogs. Although hepatotoxicity secondary to …