The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

The aging of population has become an issue of great concern because of its rapid
increase. Aging is an important risk factor of many chronic diseases. Resveratrol could be …

Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor
in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved …

Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …

Older organs represent an untapped potential to close the gap between demand and supply
in organ transplantation but are associated with age-specific responses to injury and …

Aging is a natural process, which plays a critical role in the pathogenesis of a variety of
diseases, ie, aging-related diseases, such as diabetes, osteoarthritis, Alzheimer disease …

Chondrocytes are the only cell type in normal cartilage. The pathological changes of
osteoarthritis (OA) mostly revolve around the apoptosis and dysfunction of chondrocytes …

Resveratrol, the phenolic substance isolated initially from Veratrum grandiflorum and richly
present in grapes, wine, peanuts, soy, and berries, has been attracting attention of scientists …

Mitochondrial DNA (mtDNA) damage is associated with the development of cardiovascular
diseases. Cardiac aging plays a central role in cardiovascular diseases. There is …

Aging is a major risk factor in the development of chronic diseases affecting various tissues
including the cardiovascular system, muscle and bones. Age-related diseases are a …