CryoTransformer: a transformer model for picking protein particles from Cryo-EM micrographs
Motivation Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the
structures of large protein complexes. Picking single protein particles from cryo-EM …
structures of large protein complexes. Picking single protein particles from cryo-EM …
[HTML][HTML] Structure-based protein and small molecule generation using EGNN and diffusion models: A comprehensive review
Recent breakthroughs in deep learning have revolutionized protein sequence and structure
prediction. These advancements are built on decades of protein design efforts, and are …
prediction. These advancements are built on decades of protein design efforts, and are …
[HTML][HTML] Accurate cryo-EM protein particle picking by integrating the foundational AI image segmentation model and specialized U-Net
Picking protein particles in cryo-electron microscopy (cryo-EM) micrographs is a crucial step
in the cryo-EM-based structure determination. However, existing methods trained on a …
in the cryo-EM-based structure determination. However, existing methods trained on a …
[HTML][HTML] CryoVirusDB: a labeled cryo-EM image dataset for AI-driven virus particle picking
With the advancements in instrumentation, image processing algorithms, and computational
capabilities, single-particle electron cryo-microscopy (cryo-EM) has achieved nearly atomic …
capabilities, single-particle electron cryo-microscopy (cryo-EM) has achieved nearly atomic …
CryoSegNet: accurate cryo-EM protein particle picking by integrating the foundational AI image segmentation model and attention-gated U-Net
Picking protein particles in cryo-electron microscopy (cryo-EM) micrographs is a crucial step
in the cryo-EM-based structure determination. However, existing methods trained on a …
in the cryo-EM-based structure determination. However, existing methods trained on a …
Accurate prediction of protein tertiary structural changes induced by single-site mutations with equivariant graph neural networks
Predicting the change of protein tertiary structure caused by singlesite mutations is important
for studying protein structure, function, and interaction. Even though computational protein …
for studying protein structure, function, and interaction. Even though computational protein …