Stroke remains the fifth leading cause of mortality in the United States with an annual rate of
over 128,000 deaths per year. Differences in incidence, pathogenesis, and clinical outcome …

Background Ischemic stroke (IS) is a complex and devastating vascular disease that has
become one of the leading causes of disability and mortality worldwide. Several studies …

Lipoprotein lipase (LPL) plays an important role in lipid metabolism by hydrolyzing
triglycerides in chylomicrons and very low density lipoproteins. An increasing number of …

The burden of stroke is disproportionately high in the South Asian subcontinent with South
Asian ethnicity conferring a greater risk of ischemic stroke than European ancestry …

Objective Numerous studies have investigated associations of gene polymorphisms and
circulating levels of TNF-α with ischemic stroke (IS), but the results were controversial. The …

Background Genetic variations in the genes of matrix metalloproteinases (MMPs) may play
an important role in the pathogenesis of ischemic stroke (IS). Here we investigate the …

Purpose/Aim of the study: The aim of this review is to summarize the role of genetic variants
affecting mean platelet volume (MPV) and platelet count (PLT) leading to higher platelet …

A number of studies have investigated the association between tumor necrosis factor (TNF)-
α gene polymorphisms and ischemic stroke susceptibility. However, results of different …

Numerous studies have studied the relationships between matrix metalloproteinase (MMP)
family gene polymorphisms and ischemic stroke. However, findings remain controversial …

Stroke is a global health problem and a leading cause of disability worldwide. There have
been numerable studies undertaking research on different aspects of ischaemic stroke …