[HTML][HTML] Dynamics of DNA methylation and its functions in plant growth and development

S Kumar, T Mohapatra - Frontiers in Plant Science, 2021 - frontiersin.org
Epigenetic modifications in DNA bases and histone proteins play important roles in the
regulation of gene expression and genome stability. Chemical modification of DNA base …

[HTML][HTML] Deciphering epitranscriptome: modification of mRNA bases provides a new perspective for post-transcriptional regulation of gene expression

S Kumar, T Mohapatra - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Gene regulation depends on dynamic and reversibly modifiable biological and chemical
information in the epigenome/epitranscriptome. Accumulating evidence suggests that …

The diversity and functions of plant RNA modifications: what we know and where we go from here

B Sharma, W Prall, G Bhatia… - Annual Review of Plant …, 2023 - annualreviews.org
Since the discovery of the first ribonucleic acid (RNA) modifications in transfer RNAs (tRNAs)
and ribosomal RNAs (rRNAs), scientists have been on a quest to decipher the identities and …

N6-methyladenosine RNA modification regulates strawberry fruit ripening in an ABA-dependent manner

L Zhou, R Tang, X Li, S Tian, B Li, G Qin - Genome biology, 2021 - Springer
Background Epigenetic mark such as DNA methylation plays pivotal roles in regulating
ripening of both climacteric and non-climacteric fruits. However, it remains unclear whether …

FIONA1 is an RNA N6-methyladenosine methyltransferase affecting Arabidopsis photomorphogenesis and flowering

C Wang, J Yang, P Song, W Zhang, Q Lu, Q Yu, G Jia - Genome Biology, 2022 - Springer
Abstract Background N 6-methyladenosine (m6A) mRNA modification is essential for
mammalian and plant viability. The U6 m6A methyltransferases in other species regulate S …

Machine learning: its challenges and opportunities in plant system biology

M Hesami, M Alizadeh, AMP Jones… - Applied Microbiology and …, 2022 - Springer
Sequencing technologies are evolving at a rapid pace, enabling the generation of massive
amounts of data in multiple dimensions (eg, genomics, epigenomics, transcriptomic …

Rational design of novel anticancer small-molecule RNA m6A demethylase ALKBH5 inhibitors

S Selberg, N Seli, E Kankuri, M Karelson - ACS omega, 2021 - ACS Publications
The RNA 6-N-methyladenosine (m6A) demethylase ALKBH5 has been shown to be
oncogenic in several cancer types, including leukemia and glioblastoma. We present here …

N6-methyladenosine modification underlies messenger RNA metabolism and plant development

Y Shao, CE Wong, L Shen, H Yu - Current Opinion in Plant Biology, 2021 - Elsevier
RNA modifications constitute an essential layer of gene regulation in living organisms. As
the most prevalent internal modification on eukaryotic mRNAs, N 6-methyladenosine (m 6 A) …

m6A‐mediated regulation of crop development and stress responses

L Zhou, G Gao, R Tang, W Wang… - Plant biotechnology …, 2022 - Wiley Online Library
Dynamic chemical modifications in eukaryotic messenger RNAs (mRNAs) constitute an
essential layer of gene regulation, among which N6‐methyladenosine (m6A) was unveiled …

Molecular evolution and functional modification of plant miRNAs with CRISPR

F Deng, F Zeng, Q Shen, A Abbas, J Cheng… - Trends in plant …, 2022 - cell.com
Gene editing using clustered regularly interspaced short palindromic repeat/CRISPR-
associated proteins (CRISPR/Cas) has revolutionized biotechnology and provides genetic …