Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology
There are more than 30 species of Glycyrrhiza genus extensively spread worldwide. It was
the most prescribed herb in Ancient Egyptian, Roman, Greek, East China, and the West from …
the most prescribed herb in Ancient Egyptian, Roman, Greek, East China, and the West from …
Chalcone scaffolds, bioprecursors of flavonoids: Chemistry, bioactivities, and pharmacokinetics
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …
Chalcone: a promising bioactive scaffold in medicinal chemistry
G Rajendran, D Bhanu, B Aruchamy, P Ramani… - Pharmaceuticals, 2022 - mdpi.com
Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …
Molecular mechanisms underlying the anticancer activities of licorice flavonoids
Z Zhang, L Yang, J Hou, S Tian, Y Liu - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Licorice has been commonly used in traditional Chinese
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …
[HTML][HTML] The potential of glycyrrhizin and licorice extract in combating COVID-19 and associated conditions
AA Gomaa, YA Abdel-Wadood - Phytomedicine plus, 2021 - Elsevier
Background Several recent studies have stated that glycyrrhizin and licorice extract are
present in most traditional Chinese medicine formulas used against SARS-CoV-2 in China …
present in most traditional Chinese medicine formulas used against SARS-CoV-2 in China …
A review on phytochemicals, pharmacological activities, drug interactions, and associated toxicities of licorice (Glycyrrhiza sp.)
Since the beginning, human beings have consistently been using plants and their
components for the prevention and treatment of various ailments. However, in the last few …
components for the prevention and treatment of various ailments. However, in the last few …
Traditional uses, pharmacological effects, and molecular mechanisms of licorice in potential therapy of COVID-19
Q Zhang, H Huang, M Qiu, Z Wu, Z Xin, X Cai… - Frontiers in …, 2021 - frontiersin.org
The current Coronavirus disease 2019 (COVID-19) pandemic has become a global
challenge, and although vaccines have been developed, it is expected that mild to moderate …
challenge, and although vaccines have been developed, it is expected that mild to moderate …
Licochalcone A inhibits proliferation and promotes apoptosis of colon cancer cell by targeting programmed cell death-ligand 1 via the NF-κB and Ras/Raf/MEK …
X Liu, Y Xing, M Li, Z Zhang, J Wang, MH Ri… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Glycyrrhiza glabra L., a traditional medicinal, has a history
of thousands of years. It is widely used in clinic and has been listed in Chinese …
of thousands of years. It is widely used in clinic and has been listed in Chinese …
Activation of Nrf2 signaling pathway by natural and synthetic chalcones: A therapeutic road map for oxidative stress
Introduction: Nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway plays a key
role in diverse gene expressions responsible for protection against oxidative stress and …
role in diverse gene expressions responsible for protection against oxidative stress and …
Molecular mechanisms of antiproliferative effects of natural chalcones
R Michalkova, L Mirossay, M Gazdova, M Kello… - Cancers, 2021 - mdpi.com
Simple Summary Despite the important progress in cancer treatment in the past decades,
the mortality rates in some types of cancer have not significantly decreased. Therefore, the …
the mortality rates in some types of cancer have not significantly decreased. Therefore, the …