[HTML][HTML] Nanoparticles as drug delivery systems: a review of the implication of nanoparticles' physicochemical properties on responses in biological systems

A Yusuf, ARZ Almotairy, H Henidi, OY Alshehri… - Polymers, 2023 - mdpi.com
In the last four decades, nanotechnology has gained momentum with no sign of slowing
down. The application of inventions or products from nanotechnology has revolutionised all …

[HTML][HTML] Methods of liposomes preparation: formation and control factors of versatile nanocarriers for biomedical and nanomedicine application

D Lombardo, MA Kiselev - Pharmaceutics, 2022 - mdpi.com
Liposomes are nano-sized spherical vesicles composed of an aqueous core surrounded by
one (or more) phospholipid bilayer shells. Owing to their high biocompatibility, chemical …

[HTML][HTML] Nanomaterials for cancer therapy: current progress and perspectives

Z Cheng, M Li, R Dey, Y Chen - Journal of hematology & oncology, 2021 - Springer
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …

Design of liposomes as drug delivery system for therapeutic applications

D Guimarães, A Cavaco-Paulo, E Nogueira - International journal of …, 2021 - Elsevier
Liposomes are spherical vesicles consisting of one or more concentric phospholipid bilayers
enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent a …

Non-viral vectors for RNA delivery

Y Yan, XY Liu, A Lu, XY Wang, LX Jiang… - Journal of Controlled …, 2022 - Elsevier
RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

[HTML][HTML] Nanomedicine review: Clinical developments in liposomal applications

E Beltrán-Gracia, A López-Camacho… - Cancer …, 2019 - Springer
Background In recent years, disease treatment has evolved strategies that require increase
in pharmaceutical agent's efficacy and selectivity while decreasing their toxicity in normal …

[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery

J Nel, K Elkhoury, É Velot, A Bianchi, S Acherar… - Bioactive materials, 2023 - Elsevier
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

[HTML][HTML] Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems

M Danaei, M Dehghankhold, S Ataei… - Pharmaceutics, 2018 - mdpi.com
Lipid-based drug delivery systems, or lipidic carriers, are being extensively employed to
enhance the bioavailability of poorly-soluble drugs. They have the ability to incorporate both …

Progress, challenges, and future of nanomedicine

C Zhang, L Yan, X Wang, S Zhu, C Chen, Z Gu, Y Zhao - Nano Today, 2020 - Elsevier
Nanotherapeutics exhibit unique advantages in clinical outcomes compared with
conventional small molecular drugs. The past three decades have seen intensive research …

[HTML][HTML] Current trends and challenges in the clinical translation of nanoparticulate nanomedicines: pathways for translational development and commercialization

S Hua, MBC De Matos, JM Metselaar… - Frontiers in …, 2018 - frontiersin.org
The use of nanotechnology in medicine has the potential to have a major impact on human
health for the prevention, diagnosis, and treatment of diseases. One particular aspect of the …