Reactive oxygen species regulation of autophagy in cancer: implications for cancer treatment
Reactive oxygen species (ROS) are important in regulating normal cellular processes, but
deregulated ROS contribute to the development of various human diseases including …
deregulated ROS contribute to the development of various human diseases including …
Curcumin inhibits apoptosis of chondrocytes through activation ERK1/2 signaling pathways induced autophagy
X Li, K Feng, J Li, D Yu, Q Fan, T Tang, X Yao, X Wang - Nutrients, 2017 - mdpi.com
Osteoarthritis (OA) is an inflammatory disease of load-bearing synovial joints that is currently
treated with drugs that exhibit numerous side effects and are only temporarily effective in …
treated with drugs that exhibit numerous side effects and are only temporarily effective in …
Environmental hormesis and its fundamental biological basis: Rewriting the history of toxicology
It has long been debated whether a little stress may be “good” for you. Extensive evidence
has now sufficiently accumulated demonstrating that low doses of a vast range of chemical …
has now sufficiently accumulated demonstrating that low doses of a vast range of chemical …
Autophagy, its mechanisms and regulation: implications in neurodegenerative diseases
M Moloudizargari, MH Asghari, E Ghobadi… - Ageing research …, 2017 - Elsevier
Autophagy is a major regulatory cellular mechanism which gives the cell an ability to cope
with some of the destructive events that normally occur within a metabolically living cell. This …
with some of the destructive events that normally occur within a metabolically living cell. This …
Identification of a five autophagy subtype-related gene expression pattern for improving the prognosis of lung adenocarcinoma
MY Zhang, C Huo, JY Liu, ZE Shi, WD Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Background: Autophagy plays an important role in lung adenocarcinoma (LUAD). In this
study, we aimed to explore the autophagy-related gene (ARG) expression pattern and to …
study, we aimed to explore the autophagy-related gene (ARG) expression pattern and to …
[HTML][HTML] Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease: a controversial issue
WJ Kwanten, W Martinet, PP Michielsen… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Autophagy is a mechanism involved in cellular homeostasis under basal and stressed
conditions delivering cytoplasmic content to the lysosomes for degradation to …
conditions delivering cytoplasmic content to the lysosomes for degradation to …
Apoptotic cell death induced by resveratrol is partially mediated by the autophagy pathway in human ovarian cancer cells
F Lang, Z Qin, F Li, H Zhang, Z Fang, E Hao - PloS one, 2015 - journals.plos.org
Resveratrol (trans-3, 4, 5'–trihydroxystilbene) is an active compound in food, such as red
grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human …
grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human …
Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells
HJ Kim, KE Hwang, DS Park, SH Oh, HY Jun… - Journal of translational …, 2017 - Springer
Background Shikonin, a natural naphthoquinone pigment purified from Lithospermum
erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying …
erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying …
Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies
L Yu, Z Jin, M Li, H Liu, J Tao, C Xu, L Wang… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke, mostly caused by thromboembolic or thrombotic arterial occlusions, is a
primary leading cause of death worldwide with high morbidity and disability. Unfortunately …
primary leading cause of death worldwide with high morbidity and disability. Unfortunately …
Autophagy in the lung
SW Ryter, AMK Choi - Proceedings of the American Thoracic …, 2010 - atsjournals.org
Autophagy is a cellular process for the disposal of damaged organelles or denatured
proteins through a lysosomal degradation pathway. By reducing endogenous …
proteins through a lysosomal degradation pathway. By reducing endogenous …