Reactive oxygen species (ROS) are important in regulating normal cellular processes, but
deregulated ROS contribute to the development of various human diseases including …

Osteoarthritis (OA) is an inflammatory disease of load-bearing synovial joints that is currently
treated with drugs that exhibit numerous side effects and are only temporarily effective in …

It has long been debated whether a little stress may be “good” for you. Extensive evidence
has now sufficiently accumulated demonstrating that low doses of a vast range of chemical …

Autophagy is a major regulatory cellular mechanism which gives the cell an ability to cope
with some of the destructive events that normally occur within a metabolically living cell. This …

Background: Autophagy plays an important role in lung adenocarcinoma (LUAD). In this
study, we aimed to explore the autophagy-related gene (ARG) expression pattern and to …

Autophagy is a mechanism involved in cellular homeostasis under basal and stressed
conditions delivering cytoplasmic content to the lysosomes for degradation to …

Resveratrol (trans-3, 4, 5'–trihydroxystilbene) is an active compound in food, such as red
grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human …

Background Shikonin, a natural naphthoquinone pigment purified from Lithospermum
erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying …

Ischemic stroke, mostly caused by thromboembolic or thrombotic arterial occlusions, is a
primary leading cause of death worldwide with high morbidity and disability. Unfortunately …

Autophagy is a cellular process for the disposal of damaged organelles or denatured
proteins through a lysosomal degradation pathway. By reducing endogenous …