Lithium is the prototype mood-stabilizer used for acute and long-term treatment of bipolar
disorder. Cumulated translational research of lithium indicated the drug's neuroprotective …

Background: Hemodynamic wall shear stress (WSS) exerted on the endothelium by flowing
blood determines the spatial distribution of atherosclerotic lesions. Disturbed flow (DF) with …

Autophagy (here refers to macroautophagy) is a catabolic pathway by which large protein
aggregates and damaged organelles are first sequestered into a double-membraned …

Introduction• Autophagy and disease‐Cancer‐Autophagy and cancer‐Gender differences in
cancer‐Autophagy, gender disparity and cancer‐Neurodegenerative diseases‐Gender …

Programmed cell death (PCD) is a genetically regulated process for the selective demise of
unwanted and damaged cells. Although our understanding of plant PCD pathways has …

Metabolism of carbohydrates and lipids and protein degradation occurs in the liver and
contributes to the body's homeostasis by secreting a variety of mediators. Any imbalance in …

The EGFR (epidermal growth factor receptor) signaling pathway is frequently deregulated in
many malignancies. Therefore, targeting the EGFR pathway is regarded as a promising …

The glycolytic enzyme Hexokinase (HKII) participates in tumor glycolysis and the
progression of various cancers, but its clinicopathological effect on the progression of …

Tumor necrosis factor alpha (TNFα) has been reported to induce necroptosis and
autophagy, but its mechanisms remain unclear. In this study, we found that TNFα …

Parkinson disease (PD), a prevalent neurodegenerative motor disorder, is characterized by
the rather selective loss of dopaminergic neurons and the presence of α-synuclein-enriched …