Glucocorticoids are used for the treatment of inflammatory and autoimmune diseases. While
they are effective therapy, bone loss and incident fracture risk are high. While previous …

Transmission electron microscopy (TEM) is an indispensable standard method to monitor
macroautophagy in tissue samples. Because TEM is time consuming and not suitable for …

Autophagy, or “self eating,” refers to a regulated cellular process for the lysosomal-
dependent turnover of organelles and proteins. During starvation or nutrient deficiency …

As shown in our previous study, sinomenine hydrochloride (SH), the major bioactive alkaloid
isolated from Sinomenium acutum Rehd. et Wils.(Fam. Menispermaceae), initiates the …

The review summarizes research into the highly relevant topics of cholinesterase and
amyloid aggregation inhibitors connected to tacrine congeners, both of which are associated …

Autophagy may be a major mechanism by which osteoblasts (OBs) protect against the
negative effects of chronic glucocorticoid (GC) usage. OBs are closely associated with the …

The present study aimed to test whether Hydroxysafflor yellow A (HSYA) protects the brain
microvascular endothelial cells (BMECs) injury induced by oxygen glucose deprivation …

The aim of this study was to investigate the effects of pinocembrin on brain
ischemia/reperfusion (I/R) injury and the potential involvement of autophagy activity changes …

Pulmonary exposure to cadmium, a major component of cigarette smoke, has a dramatic
impact on lung function and the development of emphysema. Cigarette smoke exposure …

Neurodegenerative diseases result in a range of conditions depending on the type of
proteinopathy, genes affected or the location of the degeneration in the brain …