Macrophage autophagy has been shown to be protective against atherosclerosis. We
previously discovered that ursolic acid (UA) promoted cancer cell autophagy. In the present …

Previous reports have shown that miR‐30d‐5p functions as a tumor suppressor in prostate
cancer and gallbladder carcinoma, but its role in renal cell carcinoma (RCC) remains …

Autophagy flux deficiency is closely related to the development of hepatic steatosis.
Transcription factor E3 (TFE3) is reported to be a crucial gene that regulates autophagy flux …

Cancer cells are highly dependent on methionine and cystine (Met–Cys) for survival and
proliferation. However, the molecular mechanism is not fully clear. The present study is to …

Autophagy is a conserved and essential intracellular mechanism for the removal of
damaged components. Since autophagy deregulation is linked to different kinds of …

Autophagy is a reparative, life-sustaining process by which cytoplasmic components are
sequestered in double membrane vesicles and degraded upon fusion with lysosomal …

Abstract Ischemia/reperfusion (I/R) is a well‐known injury to the myocardium, but the
mechanism involved remains elusive. In addition to the well‐accepted apoptosis theory …

Amyloid-β (Aβ) plays a critical role in the pathogenesis of Alzheimer's disease (AD), an age-
related neurodegenerative ailment. Emerging evidence suggests that Tenuifolin (TEN) …

Genotoxic agents have long targeted apoptotic cell death as a primary means of treating
cancer. However, the presence of cellular defects in many cancers has contributed to an …

Various small molecule pharmacologic agents with different known functions produce
similar outcomes in diverse Mendelian and complex disorders, suggesting that they may …