Autophagy regulates exosome secretion in rat nucleus pulposus cells via the RhoC/ROCK2 pathway
SQ Hu, QC Zhang, QB Meng, AN Hu, JP Zou… - Experimental cell …, 2020 - Elsevier
Our present study investigated whether exosome secretion of nucleus pulposus cells
(NPCs) is regulated by autophagy. Different autophagic states of NPCs were induced by …
(NPCs) is regulated by autophagy. Different autophagic states of NPCs were induced by …
Metabolomics analysis highlights Yashtimadhu (Glycyrrhiza glabra L.)‐mediated neuroprotection in a rotenone‐induced cellular model of Parkinson's disease by …
Parkinson's disease (PD) is an age‐associated progressive neurodegenerative movement
disorder, and its management strategies are known to cause complications with prolonged …
disorder, and its management strategies are known to cause complications with prolonged …
IL-33 provides neuroprotection through suppressing apoptotic, autophagic and NF-κB-mediated inflammatory pathways in a rat model of recurrent neonatal seizure
Y Gao, C Luo, L Li, G Ye, C Gao, H Wang… - Frontiers in molecular …, 2017 - frontiersin.org
Interleukin-33 (IL-33) is a novel identified chromatin-associated cytokine of IL-1 family
cytokines. It signals through a heterodimer comprised of ST2L and IL-1RAcp, and plays a …
cytokines. It signals through a heterodimer comprised of ST2L and IL-1RAcp, and plays a …
Transcription factor EB (TFEB)-mediated autophagy protects against ethyl carbamate-induced cytotoxicity
Y Li, X Ye, X Zheng, W Chen - Journal of hazardous materials, 2019 - Elsevier
Ethyl carbamate (EC) is thought to be a toxicant that widely exists in cigarette smoke and
polluted air, as well as fermented food and alcoholic beverages. However, the mechanism …
polluted air, as well as fermented food and alcoholic beverages. However, the mechanism …
Autophagy accompanied with bisdemethoxycurcumin-induced apoptosis in non-small cell lung cancer cells
JH Xu, HP Yang, XD Zhou, HJ Wang, G Liang… - Biomedical and …, 2015 - Elsevier
Objective To investigate the effects of bisdemethoxycurcumin (BDMC) on non-small cell lung
cancer (NSCLC) cell line, A549, and the highly metastatic lung cancer 95D cells. Methods …
cancer (NSCLC) cell line, A549, and the highly metastatic lung cancer 95D cells. Methods …
Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular …
Shikonin, a naphthoquinone derived from the Chinese medicinal plant Lithospermum
erythrorhizon, shows potential to be a cancer chemotherapeutic agent. Our previous data …
erythrorhizon, shows potential to be a cancer chemotherapeutic agent. Our previous data …
The uncoupling of autophagy and zinc homeostasis in airway epithelial cells as a fundamental contributor to COPD
E Roscioli, HB Tran, H Jersmann… - … of Physiology-Lung …, 2017 - journals.physiology.org
The proper regulation of zinc (Zn) trafficking proteins and the cellular distribution of Zn are
critical for the maintenance of autophagic processes. However, there have been no studies …
critical for the maintenance of autophagic processes. However, there have been no studies …
Macrophage migration inhibitory factor has a permissive role in concanavalin A-induced cell death of human hepatoma cells through autophagy
Concanavalin A (ConA) is a lectin and T-cell mitogen that can activate immune responses.
In recent times, ConA-induced cell death of hepatoma cells through autophagy has been …
In recent times, ConA-induced cell death of hepatoma cells through autophagy has been …
A pan-cancer assessment of alterations of the kinase domain of ULK1, an upstream regulator of autophagy
M Kumar, E Papaleo - Scientific Reports, 2020 - nature.com
Autophagy is a key clearance process to recycle damaged cellular components. One
important upstream regulator of autophagy is ULK1 kinase. Several three-dimensional …
important upstream regulator of autophagy is ULK1 kinase. Several three-dimensional …
Dihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms
M Casasampere, YF Ordóñez, J Casas… - Biochimica et Biophysica …, 2017 - Elsevier
Background Autophagy consists on the delivery of cytoplasmic material and organelles to
lysosomes for degradation. Research on autophagy is a growing field because deciphering …
lysosomes for degradation. Research on autophagy is a growing field because deciphering …