[HTML][HTML] Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction
M Ko, GT Oh, J Park, HJ Kwon - BMB reports, 2020 - ncbi.nlm.nih.gov
Danshen (Salvia miltiorrhiza) is a traditional medicinal plant widely used in Asian countries
for its pharmacological activities (eg, amelioration of cardiovascular diseases). In this study …
for its pharmacological activities (eg, amelioration of cardiovascular diseases). In this study …
Overexpression of Nrdp1 in the Heart Exacerbates Doxorubicin-Induced Cardiac Dysfunction in Mice
Y Zhang, YM Kang, C Tian, Y Zeng, LX Jia, X Ma, J Du… - PloS one, 2011 - journals.plos.org
Background Cardiac cell death and generation of oxidative stress contribute to doxorubicin
(DOX)-induced cardiac dysfunction. E3 ligase Nrdp1 plays a critical role in the regulation of …
(DOX)-induced cardiac dysfunction. E3 ligase Nrdp1 plays a critical role in the regulation of …
[HTML][HTML] PAR2 promotes high-fat diet-induced hepatic steatosis by inhibiting AMPK-mediated autophagy
BM Kim, DH Kim, YJ Park, S Ha, YJ Choi, HS Yu… - The Journal of …, 2021 - Elsevier
Abstract Protease-activated receptor 2 (PAR2) is a member of G protein-coupled receptors.
There are two types of PAR2 signaling pathways: Canonical G-protein signaling and β …
There are two types of PAR2 signaling pathways: Canonical G-protein signaling and β …
[HTML][HTML] Estrogen protects cardiomyocytes against lipopolysaccharide by inhibiting autophagy
F Wang, J Xiao, Y Shen, F Yao… - Molecular Medicine …, 2014 - spandidos-publications.com
Autophagy has a significant role in myocardial injury induced by lipopolysaccharide (LPS).
Estrogen (E2) has been demonstrated to protect cardiomyocytes against apoptosis; …
Estrogen (E2) has been demonstrated to protect cardiomyocytes against apoptosis; …
Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells
Recombinant human arginase (rhArg) has been developed for arginine derivation therapy of
cancer and is currently in clinical trials for a variety of malignant solid tumors. In this study …
cancer and is currently in clinical trials for a variety of malignant solid tumors. In this study …
Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells
The purine-derived analogs, roscovitine and purvalanol are selective synthetic inhibitors of
cyclin-dependent kinases (CDKs) induced cell cycle arrest and lead to apoptotic cell death …
cyclin-dependent kinases (CDKs) induced cell cycle arrest and lead to apoptotic cell death …
Activation of autophagy contributes to the angiotensin II-triggered apoptosis in a dopaminergic neuronal cell line
Q Gao, T Jiang, HR Zhao, L Wu, YY Tian, Z Ou… - Molecular …, 2016 - Springer
Our recent study indicated that angiotensin II (Ang II), the main component of renin-
angiotensin system, participated in the pathogenesis of Parkinson's disease (PD) by …
angiotensin system, participated in the pathogenesis of Parkinson's disease (PD) by …
[HTML][HTML] SH003 suppresses breast cancer growth by accumulating p62 in autolysosomes
Drug markets revisits herbal medicines, as historical usages address their therapeutic
efficacies with less adverse effects. Moreover, herbal medicines save both cost and time in …
efficacies with less adverse effects. Moreover, herbal medicines save both cost and time in …
Induction of autophagy enhances apoptotic cell death via epidermal growth factor receptor inhibition by canertinib in cervical cancer cells
Background It has been known epidermal growth factor receptor (EGFR) frequently
overexpressed in cervical cancer. High levels of EGFR expression in their tumors leads to a …
overexpressed in cervical cancer. High levels of EGFR expression in their tumors leads to a …
Express path analysis identifies a tyrosine kinase Src-centric network regulating divergent host responses to Mycobacterium tuberculosis infection
Global gene expression profiling has emerged as a major tool in understanding complex
response patterns of biological systems to perturbations. However, a lack of unbiased …
response patterns of biological systems to perturbations. However, a lack of unbiased …