Ferroptosis and tumor drug resistance: current status and major challenges

Z Nie, M Chen, Y Gao, D Huang, H Cao… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is a novel type of regulated cell death, whose unique metabolic characteristics
are commonly used to evaluate the conditions of various diseases especially in tumors …

Drug resistance in cancers: A free pass for bullying

J Li, X Li, Q Guo - Cells, 2022 - mdpi.com
The cancer burden continues to grow globally, and drug resistance remains a substantial
challenge in cancer therapy. It is well established that cancerous cells with clonal dysplasia …

Bioprinting and differentiation of adipose-derived stromal cell spheroids for a 3D breast cancer-adipose tissue model

H Horder, M Guaza Lasheras, N Grummel… - Cells, 2021 - mdpi.com
Biofabrication, including printing technologies, has emerged as a powerful approach to the
design of disease models, such as in cancer research. In breast cancer, adipose tissue has …

Comparative study regarding the properties of methylene blue and proflavine and their optimal concentrations for in vitro and in vivo applications

ME Nedu, M Tertis, C Cristea, AV Georgescu - Diagnostics, 2020 - mdpi.com
Methylene blue and proflavine are fluorescent dyes used to stain nucleic acid from the
molecular level to the tissue level. Already clinically used for sentinel node mapping …

Metal–Drug Coordination Nanoparticles and Hydrogels for Enhanced Delivery

KY Wong, Z Nie, MS Wong, Y Wang… - Advanced Materials, 2024 - Wiley Online Library
Drug delivery is a key component of nanomedicine, and conventional delivery relies on the
adsorption or encapsulation of drug molecules to a nanomaterial. Many delivery vehicles …

Tumor-secreted PAI-1 promotes breast cancer metastasis via the induction of adipocyte-derived collagen remodeling

X Wei, S Li, J He, H Du, Y Liu, W Yu, H Hu… - Cell communication and …, 2019 - Springer
Background Breast cancer cells recruit surrounding stromal cells, such as cancer-associated
fibroblasts (CAFs), to remodel collagen and promote tumor metastasis. Adipocytes are the …

A 3D In Vitro Triculture Hybrid Model Recapitulating Tumor Stromal Interaction of Triple‐Negative Breast Cancer as a High Throughput Anticancer Drug Screening …

C Jaiswal, BB Mandal - Advanced Therapeutics, 2024 - Wiley Online Library
Breast cancer (BC) progression is substantially driven by cellular cross‐talk between tumor
and stromal cells within the tumor microenvironment (TME). However, lack of precise …

Studying Adipose Tissue in the Breast Tumor Microenvironment In Vitro: Progress and Opportunities

D Mertz, J Sentosa, G Luker, S Takayama - Tissue Engineering and …, 2020 - Springer
Background: The breast cancer microenvironment contains a variety of stromal cells that are
widely implicated in worse patient outcomes. While many in vitro models of the breast tumor …

Age-dependent remodeling in infrapatellar fat pad adipocytes and extracellular matrix: a comparative study

E Stocco, E Belluzzi, M Contran… - Frontiers in …, 2021 - frontiersin.org
The infrapatellar fat pad (IFP) is actively involved in knee osteoarthritis (OA). However, a
proper description of which developmental modifications occur in the IFP along with age and …

Types of advanced optical microscopy techniques for breast cancer research: a review

A Dravid U, N Mazumder - Lasers in Medical Science, 2018 - Springer
A cancerous cell is characterized by morphological and metabolic changes which are the
key features of carcinogenesis. Adenosine triphosphate (ATP) in cancer cells is primarily …