Protein corona, understanding the nanoparticle–protein interactions and future perspectives: A critical review

T Kopac - International Journal of Biological Macromolecules, 2021 - Elsevier
Proteins are biopolymers of highly varied structures taking part in almost all processes
occurring in living cells. When nanoparticles (NPs) interact with proteins in biological …

Nanoparticles' interactions with vasculature in diseases

JK Tee, LX Yip, ES Tan, S Santitewagun… - Chemical Society …, 2019 - pubs.rsc.org
The ever-growing use of inorganic nanoparticles (NPs) in biomedicine provides an exciting
approach to develop novel imaging and drug delivery systems, owing to the ease with which …

To waste or not to waste: questioning potential health risks of micro-and nanoplastics with a focus on their ingestion and potential carcinogenicity

ES Gruber, V Stadlbauer, V Pichler… - Exposure and …, 2023 - Springer
Micro-and nanoplastics (MNPs) are recognized as emerging contaminants, especially in
food, with unknown health significance. MNPs passing through the gastrointestinal tract …

Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver

L Miao, J Lin, Y Huang, L Li, D Delcassian, Y Ge… - Nature …, 2020 - nature.com
Lipid-like nanoparticles (LNPs) have potential as non-viral delivery systems for mRNA
therapies. However, repeated administrations of LNPs may lead to accumulation of delivery …

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

C Corbo, R Molinaro, A Parodi… - …, 2016 - Taylor & Francis
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …

Protein corona of nanoparticles: distinct proteins regulate the cellular uptake

S Ritz, S Schöttler, N Kotman, G Baier… - …, 2015 - ACS Publications
Understanding nanoparticle–protein interactions is a crucial issue in the development of
targeted nanomaterial delivery. Besides unraveling the composition of the nanoparticle's …

Nanoparticle–cell interactions: molecular structure of the protein corona and cellular outcomes

CC Fleischer, CK Payne - Accounts of chemical research, 2014 - ACS Publications
Conspectus The use of nanoparticles (NPs) in biology and medicine requires a molecular-
level understanding of how NPs interact with cells in a physiological environment. A critical …

Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

H Mohammad-Beigi, Y Hayashi, CM Zeuthen… - Nature …, 2020 - nature.com
The current understanding of the biological identity that nanoparticles may acquire in a
given biological milieu is mostly inferred from the hard component of the protein corona …

Impact of protein pre-coating on the protein corona composition and nanoparticle cellular uptake

V Mirshafiee, R Kim, S Park, M Mahmoudi, ML Kraft - Biomaterials, 2016 - Elsevier
Nanoparticles (NPs) are functionalized with targeting ligands to enable selectively delivering
drugs to desired locations in the body. When these functionalized NPs enter the blood …

Evaluation of mesoporous silica nanoparticles for oral drug delivery–current status and perspective of MSNs drug carriers

J Florek, R Caillard, F Kleitz - Nanoscale, 2017 - pubs.rsc.org
The oral pathway is considered as the most common method for drug administration,
although many drugs, especially the highly pH-and/or enzymatic biodegradable peptide …