Nano-based drug delivery or targeting to eradicate bacteria for infection mitigation: a review of recent advances

YC Yeh, TH Huang, SC Yang, CC Chen… - Frontiers in …, 2020 - frontiersin.org
Pathogenic bacteria infection is a major public health problem due to the high morbidity and
mortality rates, as well as the increased expenditure on patient management. Although there …

Antibacterial activities with the structure-activity relationship of coumarin derivatives

HL Qin, ZW Zhang, L Ravindar, KP Rakesh - European journal of medicinal …, 2020 - Elsevier
The development of drug-resistant bacteria, as well as multidrug-resistant pathogens related
to substantial mortality, is an important global health threat. The wide range of biological …

Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation

R Verma, SK Verma, KP Rakesh, YR Girish… - European journal of …, 2021 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming lethal to humanity due to
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …

Chalcone derivatives and their antibacterial activities: Current development

M Xu, P Wu, F Shen, J Ji, KP Rakesh - Bioorganic Chemistry, 2019 - Elsevier
The increase in antibiotic resistance due to various factors has encouraged the look for
novel compounds which are active against multidrug-resistant pathogens. In this framework …

Antibacterial activities of sulfonyl or sulfonamide containing heterocyclic derivatives and its structure-activity relationships (SAR) studies: A critical review

SK Verma, R Verma, F Xue, PK Thakur, YR Girish… - Bioorganic …, 2020 - Elsevier
The rise of drug-resistance has made the deserted clinical requirement to improve of new
classes of antibiotics agents. The development of antibacterial agents with the novel method …

Recent advances in metal-organic framework-based materials for anti-staphylococcus aureus infection

M Yang, J Zhang, Y Wei, J Zhang, C Tao - Nano research, 2022 - Springer
The rapid spread of staphylococcus aureus (S. aureus) causes an increased morbidity and
mortality, as well as great economic losses in the world. Anti-S. aureus infection becomes a …

Recent accomplishments on the synthetic/biological facets of pharmacologically active 1H-1, 2, 3-triazoles

S Kumar, B Sharma, V Mehra, V Kumar - European Journal of Medicinal …, 2021 - Elsevier
The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …

Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA)

HL Qin, J Liu, WY Fang, L Ravindar… - European journal of …, 2020 - Elsevier
Antibacterial-resistance speaks to an overall alarm, particularly in regards to the flare-up of
methicillin-resistance Staphylococcus aureus (MRSA), a classic reason for genuine skin and …

Nanotools for sepsis diagnosis and treatment

L Papafilippou, A Claxton, P Dark… - Advanced …, 2021 - Wiley Online Library
Sepsis is one of the leading causes of death worldwide with high mortality rates and a
pathological complexity hindering early and accurate diagnosis. Today, laboratory culture …

Strategies for interfering with bacterial early stage biofilms

J Fu, Y Zhang, S Lin, W Zhang, G Shu, J Lin… - Frontiers in …, 2021 - frontiersin.org
Biofilm-related bacteria show high resistance to antimicrobial treatments, posing a
remarkable challenge to human health. Given bacterial dormancy and high expression of …