Abstract The Food and Drug Administration (FDA) regulates pharmaceutical drug products
to ensure a continuous supply of high-quality drugs in the USA. Continuous processing has …

The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …

This multiauthor review article aims to bring readers up to date with some of the current
trends in the field of process analytical technology (PAT) by summarizing each aspect of the …

The implementation of process analytical technology and continuous manufacturing at an
FDA approved commercial manufacturing site is described. In this direct compaction process …

Continuous bioprocessing is significantly changing the biological drugs (or biologics)
manufacturing landscape by potentially improving product quality, process stability, and …

Blend uniformity was monitored throughout a continuous manufacturing (CM) process by
near infrared (NIR) spectroscopic measurements of flowing blends and compared to the …

Pharmaceutical solid oral dosage product manufacturing is a well-established, yet
revolutionizing area. To this end, process analytical technology (PAT) involves …

It is desirable for a pharmaceutical final dosage form to be manufactured through a quality
by design (QbD)-based approach rather than a quality by testing (QbT) approach. An …

A novel manufacturing strategy based on continuous processing integrated with
online/inline monitoring tools coupled with an advanced control system is highly desired for …

Continuous manufacturing offers potential opportunities for the improved manufacturing of
pharmaceutical products. A key challenge is the development of an appropriate control …