Addressing neurodegeneration in glaucoma: Mechanisms, challenges, and treatments

GOB Ghanem, LK Wareham, DJ Calkins - Progress in Retinal and Eye …, 2024 - Elsevier
Glaucoma is the leading cause of irreversible blindness globally. The disease causes vision
loss due to neurodegeneration of the retinal ganglion cell (RGC) projection to the brain …

Effects and potential mechanisms of exercise and physical activity on eye health and ocular diseases

Q Zhang, Y Jiang, C Deng, J Wang - Frontiers in Medicine, 2024 - frontiersin.org
In the field of eye health, the profound impact of exercise and physical activity on various
ocular diseases has become a focal point of attention. This review summarizes and …

Mitophagy in Astrocytes Is Required for the Health of Optic Nerve

M Yazdankhah, S Ghosh, H Liu, S Hose, JS Zigler Jr… - Cells, 2023 - mdpi.com
Mitochondrial dysfunction in astrocytes has been implicated in the development of various
neurological disorders. Mitophagy, mitochondrial autophagy, is required for proper …

Effects of carotenoids on mitochondrial dysfunction

OS Ademowo, O Oyebode, R Edward… - Biochemical Society …, 2024 - portlandpress.com
Oxidative stress, an imbalance between pro-oxidant and antioxidant status, favouring the
pro-oxidant state is a result of increased production of reactive oxygen species (ROS) or …

Common Variants rs429358 and rs7412 in APOE Gene Are Not Associated with POAG in a Saudi Cohort

AA Kondkar, T Sultan, TA Azad, T Khatlani, AA Alshehri… - Biology, 2024 - mdpi.com
Simple Summary Glaucoma is a common eye condition linked to genes and aging. We
studied genetic factors related to primary open-angle glaucoma (POAG) in adult Arabs from …

Neuroprotective effects of resveratrol on retinal ganglion cells in glaucoma in rodents: A narrative review

M Golmohammadi, SAA Meibodi… - Animal Models and …, 2024 - Wiley Online Library
Glaucoma, an irreversible optic neuropathy, primarily affects retinal ganglion cells (RGC)
and causes vision loss and blindness. The damage to RGCs in glaucoma occurs by various …

Neuroprotective effects of resveratrol on retinal ganglion cells in glaucoma: Focusing on oxidative stress, cellular, and molecular mechanisms

M Zamanian, M Golmohammadi… - Authorea …, 2024 - advance.sagepub.com
Retinal ganglion cells (RGCs) are the major cells that are damaged in glaucoma leading to
vision loss and blindness. The damage to RGCs in glaucoma is caused by various …