Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety

MA Hannan, MA Rahman, AAM Sohag, MJ Uddin… - Nutrients, 2021 - mdpi.com
Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …

Proanthocyanidins and hydrolysable tannins: occurrence, dietary intake and pharmacological effects

A Smeriglio, D Barreca, E Bellocco… - British journal of …, 2017 - Wiley Online Library
Tannins are a heterogeneous group of high MW, water‐soluble, polyphenolic compounds,
naturally present in cereals, leguminous seeds and, predominantly, in many fruits and …

Relevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke

Q Xu, B Zhao, Y Ye, Y Li, Y Zhang, X Xiong… - Journal of …, 2021 - Springer
The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin
domain-containing 3 (NLRP3) inflammasome is a member of the NLR family of inherent …

[HTML][HTML] Mechanisms of ferroptosis regulating oxidative stress and energy metabolism in myocardial ischemia-reperfusion injury and a novel perspective of natural …

T Zhang, W Deng, Y Deng, Y Liu, S Xiao, Y Luo… - Biomedicine & …, 2023 - Elsevier
Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

Acrylamide induces ferroptosis in HSC-T6 cells by causing antioxidant imbalance of the XCT-GSH-GPX4 signaling and mitochondrial dysfunction

Y Yuan, L Yucai, L Lu, L Hui, P Yong, Y Haiyang - Toxicology Letters, 2022 - Elsevier
Acrylamide (AA) is a heat-induced food contaminant, mainly metabolized by the liver.
Increasing evidences have proved that ferroptosis is linked to the pathogenesis of liver …

Molecular mechanism of cell ferroptosis and research progress in regulation of ferroptosis by noncoding RNAs in tumor cells

B Xie, Y Guo - Cell Death Discovery, 2021 - nature.com
Ferroptosis is a newly identified form of nonapoptotic regulated cell death characterized by
iron-dependent accumulation of lipid reactive oxygen species. Morphologically and …

Molecular mechanisms of ferroptosis and its roles in hematologic malignancies

Y Zhao, Z Huang, H Peng - Frontiers in oncology, 2021 - frontiersin.org
Cell death is essential for the normal metabolism of human organisms. Ferroptosis is a
unique regulated cell death (RCD) mode characterized by excess accumulation of iron …

Ferroptosis: A potential target for the intervention of intervertebral disc degeneration

LP Zhou, RJ Zhang, CY Jia, L Kang… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis, an iron-dependent form of programmed cell death marked by phospholipid
peroxidation, is regulated by complex cellular metabolic pathways including lipid …

Global characteristics and trends in research on ferroptosis: a data‐driven bibliometric study

X Dong, Y Tan, D Zhuang, T Hu… - Oxidative medicine and …, 2022 - Wiley Online Library
Ferroptosis, an iron‐dependent form of regulated cell death, has drawn an increasing
amount of attention since it was first mentioned in 2012 and is found to play a significant role …

Oxidative stress-induced ferroptosis in cardiovascular diseases and epigenetic mechanisms

J Li, Y Zhou, H Wang, J Lou, C Lenahan… - Frontiers in Cell and …, 2021 - frontiersin.org
The recently discovered ferroptosis is a new kind of iron-regulated cell death that differs from
apoptosis and necrosis. Ferroptosis can be induced by an oxidative stress response, a …