Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII)

M Bialer, SI Johannessen, HJ Kupferberg, RH Levy… - Epilepsy research, 2007 - Elsevier
The Eigth Eilat Conference on New Antiepileptic Drugs (AEDs)-EILAT VII, took place in
Sitges, Barcelona from the 10th to 14th September, 2006. Basic scientists, clinical …

Development of new antiepileptic drugs: challenges, incentives, and recent advances

E Perucca, J French, M Bialer - The lancet neurology, 2007 - thelancet.com
Despite the introduction of many second-generation antiepileptic drugs (AEDs) in the past
15 years, a third of patients with epilepsy remain refractory to available treatments, and …

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures: a randomized, double‐blind, placebo‐controlled …

C Elger, P Halász, J Maia, L Almeida… - …, 2009 - Wiley Online Library
Purpose: To study the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive
therapy for refractory partial seizures in adults with≥ 4 partial‐onset seizures (simple or …

Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions

JJ Łuszczki - Pharmacological reports, 2009 - Elsevier
This review briefly summarizes the information on the molecular mechanisms of action,
pharmacokinetic profiles and drug interactions of novel (third-generation) antiepileptic …

Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy

E Ben-Menachem, AA Gabbai, A Hufnagel, J Maia… - Epilepsy research, 2010 - Elsevier
OBJECTIVE: To investigate the efficacy and safety of once-daily eslicarbazepine acetate
(ESL) when used as add-on treatment in adults with≥ 4 partial-onset seizures per 4-week …

Pharmacokinetics and drug interactions of eslicarbazepine acetate

M Bialer, P Soares‐da‐Silva - Epilepsia, 2012 - Wiley Online Library
Eslicarbazepine acetate (ESL) is a novel once‐daily antiepileptic drug (AED) approved in
Europe since 2009 that was found to be efficacious and well tolerated in a phase III clinical …

Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures

A Gil‐Nagel, J Lopes‐Lima, L Almeida… - Acta Neurologica …, 2009 - Wiley Online Library
Objectives–To evaluate the efficacy and safety of eslicarbazepine acetate (ESL) as
adjunctive therapy in adults with partial‐onset seizures. Material and methods–Double …

Placebo‐corrected efficacy of modern antiepileptic drugs for refractory epilepsy: systematic review and meta‐analysis

S Beyenburg, K Stavem, D Schmidt - Epilepsia, 2010 - Wiley Online Library
Although adjunctive treatment with modern antiepileptic drugs (AEDs) is standard care in
refractory epilepsy, it is unclear how much of the effect can be attributed directly to the AEDs …

[HTML][HTML] Efficacy, tolerability and safety of add-on third-generation antiseizure medications in treating focal seizures worldwide: a network meta-analysis of randomised …

Y Chen, W Li, C Lu, X Gao, H Song, Y Zhang… - …, 2024 - thelancet.com
Background Adjunctive newer antiseizure medications (ASMs) are being used in patients
with treatment-resistant focal-onset seizures (FOS). An updated network meta-analysis …

Epilepsy in the elderly: facts and challenges

H Stefan - Acta Neurologica Scandinavica, 2011 - Wiley Online Library
Stefan H. Epilepsy in the elderly: facts and challenges. Acta Neurol Scand: 2011: 124: 223–
237.© 2010 John Wiley & Sons A/S. The incidence of epilepsy in the elderly has increased …