The binding interactions of three kinds of tyrosine kinase inhibitors (TKIs), such as gefitinib,
lapatinib and sunitinib, with bovine serum albumin (BSA) were studied using ultraviolet …

Lenvatinib was a multi-tyrosine kinase inhibitor (TKI) used for treating advanced renal cell
carcinoma and differentiated thyroid cancer. Multiple fluorescence spectroscopy including …

The binding studies of DNA with small molecules have been an emerging field of research
all the time since DNA as the genetic material is a major biological target for various drugs …

Simple Summary Cancer is one of the biggest causes of death world-wide. The
development of anti-cancer drugs is important in combatting this disease. As good as these …

In this investigation, the effects of candidone on the structure and conformation of DNA were
evaluated by spectroscopic methods, molecular dynamics simulation, and molecular …

Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) is a first-line targeted
drug for the treatment of advanced non-small cell lung cancer (NSCLC) in clinical practice …

The thalidomide-DNA interactions have been investigated in detail by numerous biophysical
techniques such as UV‐vis, dye displacement assay, viscosity, cyclic voltammetry, circular …

One of the most important mechanism by which bioflavonoids can exert their effects in
cancer treatment, is through their interaction with bio-macromolecules such as DNA. Recent …

In this study, synthesis of 15 novel bis indole‐based Schiff bases (SBs) 4a–4o was
conducted by condensation of 2‐(1‐aminobenzyl) benzimidazole with symmetrical bis …

Pendimethalin (PND) is a systemic herbicide widely used on rice, cotton, peas, wheat,
potatoes, fruits, nuts and other residential and non-residential crops; however, it concurrently …