Mechanism and implications of CXCR4‐mediated integrin activation by Porphyromonas gingivalis

G Hajishengallis, ML McIntosh… - Molecular oral …, 2013 - Wiley Online Library
In monocytes and macrophages, the interaction of Porphyromonas gingivalis with Toll‐like
receptor 2 (TLR 2) leads to the activation of a MyD88‐dependent antimicrobial pathway and …

The role of pili in Bacillus cereus intraocular infection

MC Callegan, SM Parkunan, CB Randall… - Experimental eye …, 2017 - Elsevier
Bacterial endophthalmitis is a potentially blinding intraocular infection. The bacterium
Bacillus cereus causes a devastating form of this disease which progresses rapidly …

A novel pathway of rapid TLR-triggered activation of integrin-dependent leukocyte adhesion that requires Rap1 GTPase

KJ Chung, I Mitroulis, JR Wiessner… - Molecular biology of …, 2014 - Am Soc Cell Biol
Rapid β2-integrin activation is indispensable for leukocyte adhesion and recruitment to sites
of infection and is mediated by chemokine-or P-selectin glycoprotein ligand-1–induced …

[HTML][HTML] Differential involvement of the canonical and noncanonical inflammasomes in the immune response against infection by the periodontal bacteria …

KQ De Andrade, CLC Almeida-da-Silva… - Current Research in …, 2021 - Elsevier
We examined the involvement of the P2× 7 receptor and the canonical and noncanonical
inflammasomes in the control of single-species or dual-species infection by the periodontal …

Free lipid A isolated from Porphyromonas gingivalis lipopolysaccharide is contaminated with phosphorylated dihydroceramide lipids: recovery in diseased dental …

FC Nichols, B Bajrami, RB Clark, W Housley… - Infection and …, 2012 - Am Soc Microbiol
Recent reports indicate that Porphyromonas gingivalis mediates alveolar bone loss or
osteoclast modulation through engagement of Toll-like receptor 2 (TLR2), though the factors …

Emerging role of high mobility group box 1 in ANCA-associated vasculitis

C Wang, AWS de Souza, J Westra, M Bijl, M Chen… - Autoimmunity …, 2015 - Elsevier
High mobility group box 1 (HMGB1) has been suggested to be involved in the pathogenesis
of many autoimmune diseases. In addition to its nuclear functions, extracellular HMGB1 …

Arabinosylated Lipoarabinomannan—mediated protection in visceral Leishmaniasis through up-regulation of toll-like receptor 2 signaling: an immunoprophylactic …

P Bhattacharya, S Bhattacharjee… - The journal of …, 2010 - academic.oup.com
Visceral leishmaniasis is characterized by severe immunosuppression of the host cell,
resulting in loss of the proinflammatory response. Toll-like receptor 2 (TLR2) is involved in …

Distribution of Porphyromonas gingivalis fimA genotypes in patients affected by rheumatoid arthritis and periodontitis

JL Ayala-Herrera, C Abud-Mendoza… - Acta Odontologica …, 2018 - Taylor & Francis
Objective: To determine and compare the distribution of Porphyromonas gingivalis fimA
genotypes in patients affected by Rheumatoid arthritis (RA) and periodontitis (PE). Materials …

Toll-like receptor-2 plays a fundamental role in periodontal bacteria-accelerated abdominal aortic aneurysms

N Aoyama, J Suzuki, M Ogawa, R Watanabe… - Circulation …, 2013 - jstage.jst.go.jp
Background: Periodontopathic bacteria are detected at a high rate in specimens obtained
from the aortic walls of patients with abdominal aortic aneurysm (AAA) and are involved in …

Distinct Signaling Pathways Between Human Macrophages and Primary Gingival Epithelial Cells by Aggregatibacter actinomycetemcomitans

ES Ando-Suguimoto, MR Benakanakere, MPA Mayer… - Pathogens, 2020 - mdpi.com
In aggressive periodontitis, the dysbiotic microbial community in the subgingival crevice,
which is abundant in Aggregatibacter actinomycetemcomitans, interacts with extra-and …