The process of senescence (aging) is predominantly determined by the action of wild-type
genes. For most organisms, this does not reflect any adaptive function that senescence …

The aging process is driven by a finite number of inter‐related mechanisms that ultimately
lead to the emergence of characteristic phenotypes, including increased susceptibility to …

From the dawn of civilization, humanity has dreamed of immortality. So why didn't the
discovery of the anti-aging properties of mTOR inhibitors change the world forever? I will …

COVID-19 is not deadly early in life, but mortality increases exponentially with age, which is
the strongest predictor of mortality. Mortality is higher in men than in women, because men …

Despite tremendous progress in recent years, our understanding of the evolution of ageing
is still incomplete. A dominant paradigm maintains that ageing evolves due to the competing …

Ageing phenotypes, such as years lived in good health (healthspan), total years lived
(lifespan), and survival until an exceptional old age (longevity), are of interest to us all but …

Garlic supplements have shown promise in the treatment of uncontrolled hypertension,
lowering blood pressure (BP) by about 10 mmHg systolic and 8 mmHg diastolic, similar to …

Synapses are functionally distinct neuronal compartments that are critical for brain function,
with synaptic dysfunction being an early pathological feature in aging and disease. Given …

Hallmarks of cancer and hallmarks of aging - PMC Back to Top Skip to main content NIH
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Over the last 50 years, major improvements have been made in our understanding of the
driving forces, both parallel and opposing, that lead to aging and cancer. Many theories on …