The dietary isoflavone daidzein mitigates oxidative stress, apoptosis, and inflammation in CDDP‐induced kidney injury in rats: Impact of the MAPK signaling pathway
A Tomar, S Kaushik, SI Khan, K Bisht… - … of Biochemical and …, 2020 - Wiley Online Library
Cisplatin‐induced nephrotoxicity persists as a clinical problem despite several supportive
measures to alleviate renal damage. Daidzein (DZ), a dietary isoflavone having antioxidant …
measures to alleviate renal damage. Daidzein (DZ), a dietary isoflavone having antioxidant …
Effect of daidzein on cisplatin-induced hematotoxicity and hepatotoxicity in experimental rats
S Karale, JV Kamath - Indian journal of pharmacology, 2017 - journals.lww.com
Objective: The objective of the study was to investigate the effect of daidzein flavonoid on
cisplatin (CP)-induced hematotoxicity and hepatotoxicity in experimental rats. Materials and …
cisplatin (CP)-induced hematotoxicity and hepatotoxicity in experimental rats. Materials and …
Treadmill exercise promotes neurogenesis in ischemic rat brains via caveolin-1/VEGF signaling pathways
Y Zhao, Q Pang, M Liu, J Pan, B Xiang, T Huang… - Neurochemical …, 2017 - Springer
Using a model of middle cerebral artery occlusion (MCAO), we have previously
demonstrated that treadmill exercise promotes angiogenesis in the ischemic penumbra …
demonstrated that treadmill exercise promotes angiogenesis in the ischemic penumbra …
Daidzein and its effects on brain
T Ahmed, S Javed, A Tariq, G Onofrio… - Current medicinal …, 2017 - ingentaconnect.com
Among naturally occurring isoflavones, soy isoflavones are an important class with various
biological activities. Due to their phytoestrogenic structure, their effects on the brain are …
biological activities. Due to their phytoestrogenic structure, their effects on the brain are …
Anti‐neuroinflammatory effect of daidzein in human hypothalamic GnRH neurons in an in vitro membrane‐based model
Phytoestrogens can control high‐fat diet‐induced hypothalamic inflammation that is
associated with severe consequences, including obesity, type 2 diabetes, cardiovascular …
associated with severe consequences, including obesity, type 2 diabetes, cardiovascular …
Chungkookjang, a soy food, fermented with Bacillus amyloliquefaciens protects gerbils against ishcmeic stroke injury, and post-stroke hyperglycemia
SY Jeong, T Zhang, X Wu, JY Qiu, S Park - Food research international, 2020 - Elsevier
Chungkookjang is a traditional Korean fermented soybean food with anti-diabetic and
thrombolytic activity. It may also have anti-stroke activity. We determined that chungkookjang …
thrombolytic activity. It may also have anti-stroke activity. We determined that chungkookjang …
[HTML][HTML] Bifidobacterium breve CCFM1025 Improves Sleep Quality via Regulating the Activity of the HPA Axis: A Randomized Clinical Trial
Y Lan, J Lu, G Qiao, X Mao, J Zhao, G Wang, P Tian… - Nutrients, 2023 - mdpi.com
Psychobiotics, a newly identified category of probiotics primarily targeting the gut–brain axis,
exhibit tremendous potential in improving sleep quality. In this study, the clinical trial was …
exhibit tremendous potential in improving sleep quality. In this study, the clinical trial was …
[HTML][HTML] Protective effect of daidzein against diethylnitrosamine/carbon tetrachloride-induced hepatocellular carcinoma in male rats
Simple Summary Hepatocellular carcinoma (HCC) claims the second-largest number of
casualties among all forms of cancer. Several chemotherapeutic agents are being used for …
casualties among all forms of cancer. Several chemotherapeutic agents are being used for …
[HTML][HTML] Phytoestrogen isoflavone intervention to engage the neuroprotective effect of glutamate oxaloacetate transaminase against stroke
In the pathophysiologic setting of cerebral ischemia, excitotoxic levels of glutamate
contribute to neuronal cell death. Our previous work demonstrated the ability of glutamate …
contribute to neuronal cell death. Our previous work demonstrated the ability of glutamate …
Soy isoflavone daidzein protects Neuro2a cells from NO stress via activation of AMPK-PGC1α pathway followed by mitochondrial enhancement
S Ito, H Sasaki, T Gotow, I Suetake, K Nagai - PharmaNutrition, 2023 - Elsevier
Background Soy isoflavone daidzein protects cells from oxidative stress. Oxidative stress
causes several neurodegenerative diseases via damaging mitochondria and inducing cell …
causes several neurodegenerative diseases via damaging mitochondria and inducing cell …