[HTML][HTML] Manufacturing different types of solid dispersions of BCS class iv polyphenol (daidzein) by spray drying: Formulation and bioavailability

GP Panizzon, F Giacomini Bueno, T Ueda-Nakamura… - Pharmaceutics, 2019 - mdpi.com
Daidzein (DZ) is a polyphenolic compound belonging to Biopharmaceutical Classification
System class IV, which shows that it may have limited therapeutic effects due to its low …

Antiherpes evaluation of soybean isoflavonoids

DF Argenta, IT Silva, VL Bassani, LS Koester… - Archives of …, 2015 - Springer
The antiviral effects of soybean isoflavonoids have been investigated recently, especially
those of genistein. It has been reported that this isoflavone is able to inhibit herpes simplex …

[HTML][HTML] Paradigms and mechanisms of inhalational anesthetics mediated neuroprotection against cerebral ischemic stroke

H Wang, P Li, N Xu, L Zhu, M Cai, W Yu… - Medical gas …, 2016 - journals.lww.com
Cerebral ischemic stroke is a leading cause of serious long-term disability and cognitive
dysfunction. The high mortality and disability of cerebral ischemic stroke is urging the health …

Sevoflurane: an opportunity for stroke treatment

J Xu, Y Ye, H Shen, W Li, G Chen - Medical Gas Research, 2023 - journals.lww.com
In developed countries, stroke is the leading cause of death and disability that affects long-
term quality of life and its incidence is increasing. The incidence of ischemic stroke is much …

Unveiling the neuroprotective properties of isoflavones: current evidence, molecular mechanisms and future perspectives

G Gong, K Ganesan, Y Wan, Y Liu… - Critical Reviews in …, 2024 - Taylor & Francis
Neurodegenerative diseases encompass a wide range of debilitating and incurable brain
disorders characterized by the progressive deterioration of the nervous system's structure …

[HTML][HTML] Bioactive flavonoids and catechols as Hif1 and Nrf2 protein stabilizers-implications for Parkinson's disease

NA Smirnova, NA Kaidery, DM Hushpulian… - Aging and …, 2016 - ncbi.nlm.nih.gov
Flavonoids are known to trigger the intrinsic genetic adaptive programs to hypoxic or
oxidative stress via estrogen receptor engagement or upstream kinase activation. To reveal …

Oenanthe javanica extract protects against experimentally induced ischemic neuronal damage via its antioxidant effects

JH Park, JH Cho, IH Kim, JH Ahn, JC Lee… - Chinese Medical …, 2015 - journals.lww.com
Background: Water dropwort (Oenanthe javanica) as a popular traditional medicine in Asia
shows various biological properties including antioxidant activity. In this study, we firstly …

Daidzein attenuates ovariectomy-induced cognitive deficits by improving cortical endothelial function in rats

S Jaiswal, A Goyal, D Garabadu - Revista Brasileira de Farmacognosia, 2023 - Springer
There have been reports of decreased vascular activity in memory-sensitive brain areas,
which is thought to be a different approach to managing cognitive deficiencies in females …

[HTML][HTML] Daidzein ameliorates spinal cord ischemia/reperfusion injury‑induced neurological function deficits in Sprague-Dawley rats through PI3K/Akt signaling …

F Zhang, N Ru, ZH Shang… - Experimental and …, 2017 - spandidos-publications.com
Daidzein (DZ) has a broad spectrum of biological activities, including antioxidant, anti‑
inflammatory and anticancer as well as cardio‑and hepatoprotective properties. The present …

[HTML][HTML] Alteration in memory cognition due to activation of caveolin-1 and oxidative damage in a model of dementia of Alzheimer's type

A Gupta, A Sharma, A Kumar… - Indian Journal of …, 2019 - journals.lww.com
OBJECTIVE: The present study aims to investigate the role of caveolin-1 in dementia of
Alzheimer's type using intracerebroventricular streptozotocin (ICV-STZ)-induced …