Endurance exercise training attenuates the waterpipe smoke inhaling-induced learning and memory impairment in Rats: Role of neurotrophic factors and apoptotic …

M Taghipour, S Joukar, S Sadat Alavi… - Nicotine and …, 2023 - academic.oup.com
Introduction The increasing prevalence of waterpipe tobacco smoking (WTS) and its
detrimental effects on memory function have been reported. This study was conducted to …

[HTML][HTML] Structural changes observed in the piriform cortex in a rat model of pre-motor Parkinson's disease

M Sancandi, EV Schul, G Economides… - Frontiers in cellular …, 2018 - frontiersin.org
Early diagnosis of Parkinson's disease (PD) offers perhaps, the most promising route to a
successful clinical intervention, and the use of an animal model exhibiting symptoms …

Intrahippocampal 5-HT1A receptor antagonist inhibits the improving effect of low-frequency stimulation on memory impairment in kindled rats

A Gharib, A Komaki, HM Khoshinani, M Saidijam… - Brain research …, 2019 - Elsevier
In addition to its anticonvulsant effect, low frequency stimulation (LFS) improves learning
and memory in kindled animals. In the present study, the role of 5-HT 1A receptors in …

Transcranial direct current stimulation of the prefrontal cortex improves depression-like behaviors in rats with Parkinson's disease

L Zhang, Y Guo, J Liu, L Li, Y Wang, X Wu, Y Bai, J Li… - Brain Research, 2024 - Elsevier
Depression associated with Parkinson's disease (PD) seriously affects patients, and there is
a lack of effective treatments. Transcranial direct current stimulation (tDCS) is increasingly …

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome

SN Amin, SA Shaltout, WB El Gazzar, NSA Latif… - Advances in Medical …, 2024 - Elsevier
Abstract Purpose Metabolic syndrome (MetS) is a common disorder associated with
disturbed neurotransmitter homeostasis. Memantine, an N-methyl-d-aspartate receptor …

Neuroactive Steroids, Toll-like Receptors, and Neuroimmune Regulation: Insights into Their Impact on Neuropsychiatric Disorders

I Balan, G Boero, SL Chéry, MH McFarland, AG Lopez… - Life, 2024 - mdpi.com
Pregnane neuroactive steroids, notably allopregnanolone and pregnenolone, exhibit
efficacy in mitigating inflammatory signals triggered by toll-like receptor (TLR) activation …

Combined metabolic activators improve cognitive functions without altering motor scores in Parkinson's disease

B Yulug, O Altay, X Li, L Hanoglu, S Cankaya, S Lam… - medRxiv, 2021 - medrxiv.org
The neuropathologic hallmarks of Parkinson's disease (PD) are associated with
mitochondrial dysfunction and metabolic abnormalities. We have reported that the …

[HTML][HTML] Neurosteroids and their potential as a safer class of general anesthetics

H Tateiwa, AS Evers - Journal of Anesthesia, 2024 - Springer
Neurosteroids (NS) are a class of steroids that are synthesized within the central nervous
system (CNS). Various NS can either enhance or inhibit CNS excitability and they play …

Implication of nigral dopaminergic lesion and repeated L-dopa exposure in neuropsychiatric symptoms of Parkinson's disease

S Loiodice, HW Young, B Rion, B Méot… - Behavioural Brain …, 2019 - Elsevier
This study aims to investigate the contribution of nigral dopaminergic (DA) cell loss,
repeated exposure to DA medication and the combination of both to the development of …

Fluoxetine tunes the abnormal hippocampal oscillations in association with cognitive impairments in 6-OHDA lesioned rats

W Liu, R Zhang, H Feng, H Zhu - Behavioural Brain Research, 2021 - Elsevier
Cognitive decline is a common clinical symptom in Parkinson's disease (PD) patients.
Fluoxetine (FLU), a selective serotonin reuptake inhibitor, can improve cognitive deficits in …