The nonsteroidal anti‐inflammatory agent aspirin is widely used for preventing and treating
cardiovascular and cerebrovascular diseases. In addition, epidemiologic evidences reveal …

Enhanced cancer treatment remains as one of the focused areas for researchers around the
world. Hence, the progress in this direction will be a challenge and an opportunity in, inter …

Simple Summary The cellular mechanisms of drug resistance prevent the correct efficacy of
the therapies used in various types of cancer and nanotechnology has been postulated as a …

Two ATP-binding cassette transporters, ABCB1/MDR1 and ABCG2/BCRP, are considered
the most critical determinants for chemoresistance in hepatocellular carcinoma. However …

An elegant approach to unknown secosteroid–quinoline hybrids is disclosed. A series of 13,
17-secoestra-1, 3, 5 (10)-trien-17-oic acid [N′-(iso) quinolylmethylene] hydrazides was …

Primary liver cancer [hepatocellular carcinoma (HCC)] is one of the most common malignant
tumors worldwide, causing serious health threats because of its high morbidity and mortality …

Multidrug resistance (MDR) is common in patients and has been linked to transforming
growth factor‐β1 (TGF‐β1) and overexpression of drug efflux transporters P‐glycoprotein (P …

Background Chemoresistance is a major obstacle to improving the survival rate of colorectal
cancer (CRC) patients. Forkhead box protein C2 (FOXC2), a member of the forkhead box …

Background The multi-drug resistance is an inherent weakness in the chemotherapeutics of
non-small cell lung cancer occurring frequently all over the world. Clinically, ginseng and …

Hepatocellular carcinoma (HCC) is the third most common cause of death from cancer
worldwide. Therapeutic strategies are still challenging due to the high relapse rate after …