[HTML][HTML] A SARS-CoV-2 NSP7 homolog of a Treg epitope suppresses CD4+ and CD8+ T cell memory responses
SMS Miah, S Lelias, AH Gutierrez, M McAllister… - Frontiers in …, 2023 - frontiersin.org
Pathogens escape host defenses by T-cell epitope mutation or deletion (immune escape)
and by simulating the appearance of human T cell epitopes (immune camouflage). We …
and by simulating the appearance of human T cell epitopes (immune camouflage). We …
[HTML][HTML] Antigenicity and immunogenicity of different morphological forms of Borrelia burgdorferi sensu lato spirochetes
K Sloupenska, B Koubkova, P Horak, J Dolezilkova… - Scientific Reports, 2024 - nature.com
Borrelia burgdorferi sensu lato is a species complex of pleomorphic spirochetes, including
species that cause Lyme disease (LD) in humans. In addition to classic spiral forms, these …
species that cause Lyme disease (LD) in humans. In addition to classic spiral forms, these …
Identification of disease-specific TCRs maintaining pathogenic T helper cell responses in postinfectious Lyme Arthritis
J Dirks, J Fischer, J Klaussner, C Hofmann… - medRxiv, 2024 - medrxiv.org
Background: Antibiotic-Refractory Lyme Arthritis (ARLA) involves a complex interplay of T
cell responses targeting Borrelia burgdorferi antigens succeeding towards autoantigens by …
cell responses targeting Borrelia burgdorferi antigens succeeding towards autoantigens by …
[HTML][HTML] Human leukocyte antigen HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis
JR Rouse, R Danner, A Wahhab, M Pereckas… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Background: HLA-DR-expressing fibroblast-like synoviocytes (FLS) are a prominent cell
type in synovial tissue in chronic inflammatory forms of arthritis. We recently showed that …
type in synovial tissue in chronic inflammatory forms of arthritis. We recently showed that …
HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis
JR Rouse, R Danner, A Wahhab, M Pereckas… - bioRxiv, 2023 - biorxiv.org
Background: HLA-DR-expressing fibroblast-like synoviocytes (FLS) are a prominent cell
type in synovial tissue in chronic inflammatory forms of arthritis. We recently showed that …
type in synovial tissue in chronic inflammatory forms of arthritis. We recently showed that …