Comparative biology of sperm factors and fertilization‐induced calcium signals across the animal kingdom

J Kashir, R Deguchi, C Jones… - Molecular …, 2013 - Wiley Online Library
Fertilization causes mature oocytes or eggs to increase their concentrations of intracellular
calcium ions (Ca2+) in all animals that have been examined, and such Ca2+ elevations, in …

Cell cycle arrest and activation of development in marine invertebrate deuterostomes

V Costache, A McDougall, R Dumollard - Biochemical and Biophysical …, 2014 - Elsevier
Like most metazoans, eggs of echinoderms and tunicates (marine deuterostomes, there is
no data for the cephalochordates) arrest awaiting fertilization due to the activity of the …

Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration

B Hu, C Shi, C Xu, P Cao, Y Tian, Y Zhang, L Deng… - Scientific reports, 2016 - nature.com
Intervertebral disc degeneration (IDD) is characterized by disordered extracellular matrix
(ECM) metabolism, implicating subdued anabolism and enhanced catabolic activities in the …

Spawning-Induced pH Increase Activates Sperm Attraction and Fertilization Abilities in Eggs of the Ascidian, Phallusia philippinensis and Ciona intestinalis

N Sensui, Y Itoh, N Okura, K Shiba, SA Baba… - International Journal of …, 2023 - mdpi.com
In Phlebobranchiata ascidians, oocytes and spermatozoa are stored in the oviduct and
spermiduct, respectively, until spawning occurs. Gametes in the gonoducts are mature and …

mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition

RC Zamfirescu, ML Day… - American Journal of …, 2021 - journals.physiology.org
Development of the mammalian preimplantation embryo is influenced by
autocrine/paracrine factors and the availability of nutrients. Deficiencies of these during in …

Blockage of KCa3. 1 and Kv1. 3 channels of the B lymphocyte decreases the inflammatory monocyte chemotaxis

S Zhang, X Wang, C Ju, L Zhu, Y Du, C Gao - International …, 2016 - Elsevier
Objective To investigate the effects of Ca 2+ activated potassium channel K Ca 3.1 and
voltage-gated potassium channel Kv1. 3 of B lymphocyte on inflammatory monocytes …

[PDF][PDF] Pharmacological research progress of ursolic acid for the treatment of liver diseases

Y Liang, Q Niu, Y Zhao - Tradit. Med. Res, 2021 - tmrjournals.com
Ursolic acid is a natural pentacyclic triterpenoid with various pharmacological activities such
as anti-inflammatory, hepatoprotective, antitumor, and hypoglycemic activity. This natural …

Release from meiotic arrest in ascidian eggs requires the activity of two phosphatases but not CaMKII

M Levasseur, R Dumollard, JP Chambon… - …, 2013 - journals.biologists.com
The fertilising sperm triggers a transient Ca2+ increase that releases eggs from cell cycle
arrest in the vast majority of animal eggs. In vertebrate eggs, Erp1, an APC/Ccdc20 inhibitor …

Artificial activation of mature unfertilized eggs in the malaria vector mosquito, Anopheles stephensi (Diptera, Culicidae)

DS Yamamoto, M Hatakeyama… - Journal of …, 2013 - journals.biologists.com
In the past decade, many transgenic lines of mosquitoes have been generated and
analyzed, whereas the maintenance of a large number of transgenic lines requires a great …

[HTML][HTML] Non-centrosomal microtubule structures regulated by egg activation signaling contribute to cytoplasmic and cortical reorganization in the ascidian egg

T Goto, K Kanda, T Nishikata - Developmental biology, 2019 - Elsevier
In the first ascidian cell cycle, cytoplasmic and cortical reorganization is required for
distributing maternal factors to their appropriate positions, resulting in the formation of the …