Thymoquinone (TQ) possesses anticonvulsant, antianxiety, antidepressant, and
antipsychotic properties. It could be utilized to treat drug misuse or dependence, and those …

Evidence from epidemiological studies has demonstrated that the incidence and mortality of
cardiovascular diseases (CVDs) increase year by year, which pose a great threat on social …

In recent years, experimental evidence suggested a possible role of the gut microbiota in the
onset and development of several neurodegenerative disorders, such as AD and PD, MS …

An increasing number of the population all around the world suffer from age-associated
neurodegenerative diseases including Parkinson's disease (PD). This disorder presents …

Gastric cancer (GC) is often diagnosed in the advanced stages with a poor prognosis.
Thymoquinone (TQ) is known for its antitumor activity; however, the specific mechanism in …

Parkinson's disease is among the most common forms of neurodegenerative illness, with
present treatment being primarily symptomatic and frequently coming with substantial …

Background: Metabolic syndrome (METS) is a set of unhealthy medical conditions
considered essential health problems today. Cinnamaldehyde (CA) is the major …

Paraquat (PQ) is a nonselective herbicide that induces oxidative reactions and multiple-
organ failure on exposure. Crocin, a carotenoid obtained from saffron, has demonstrated …

Background Alpha-synuclein (α-syn) aggregates contribute to neuronal damage and many
neurodegenerative disorders (NDs) which are known as α-synucleinopathies. Flavonoids …

Abstract Traditional Chinese Medicine (TCM) is widely used in clinical practice to treat
diseases related to central nervous system (CNS) damage. However, the blood‐brain …