Curcumin diffuses through cell membranes into the endoplasmic reticulum, mitochondria,
and nucleus, where it exerts actions, as an antioxidant property. Therefore, its use has been …

In recent years, nutraceuticals have gained great popularity, owing to their physiological and
potential health effects, such as anti-inflammatory, anti-cancer, antioxidant, and prebiotic …

Objective: Our objective was to provide a scholarly review of the published literature on
menopausal hormonal therapy (MHT), make scientifically valid assessments of the available …

A myriad of physiological processes in mammals are influenced by estrogens and the
estrogen receptors (ERs), ERα and ERβ. As we reviewed previously, given the widespread …

Colorectal cancer (CRC) is a leading cause of death in the United States. Despite its slow
development and the capacity for early diagnosis, current preventive approaches are not …

Phytoestrogens are natural substances that have been extensively studied for their
beneficial effect on human health. Herein, we analyzed the data of the literature on the role …

The colon is the largest hormonally active tissue in the human body. It has been known for
over a hundred years that various hormones and bioactive peptides play important roles in …

Familial adenomatous polyposis (FAP) is a genetic syndrome characterized by the presence
of multiple polyps in the gastrointestinal tract and a wide range of systemic extra-intestinal …

Colorectal cancer (CRC) is the second cause of cancer-related death in both sexes
worldwide. As pre-menopausal women are less likely to develop CRC compared to age …

Numerous clinical and animal studies show that hormone replacement therapy reduces the
risk of colon tumor formation. However, the majority of experiments have shown that …