[HTML][HTML] Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations

Z Ali, JM Godoy-Corchuelo… - Disease Models & …, 2023 - journals.biologists.com
Variants in the ubiquitously expressed DNA/RNA-binding protein FUS cause aggressive
juvenile forms of amyotrophic lateral sclerosis (ALS). Most FUS mutation studies have …

[HTML][HTML] Age-related changes in species-typical behaviours in the 5xFAD mouse model of Alzheimer's disease from 4 to 16 months of age

TP O'Leary, RE Brown - Behavioural Brain Research, 2024 - Elsevier
Alzheimer's disease (AD) patients show age-related decreases in the ability to perform
activities of daily living and the decline in these activities is related to the severity of …

[HTML][HTML] Apathy-like behaviour in tau mouse models of Alzheimer's disease and frontotemporal dementia

L Robinson, E Dreesen, M Mondesir… - Behavioural Brain …, 2024 - Elsevier
Apathy is the most common behavioural and psychological symptom in Alzheimer's disease
(AD) and other neurodegenerative diseases including frontotemporal dementia (FTD) and …

Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer disease mouse model via enhancing neurotrophic and synaptic signaling

HB Taha, A Birnbaum, I Matthews, K Aceituno, J Leon… - bioRxiv, 2024 - biorxiv.org
INTRODUCTION: Skeletal muscle regulates central nervous system (CNS) function and
health, activating the muscle-to-brain axis through the secretion of skeletal muscle …

Aberrant Behaviour and Neural Activity in the 5xFAD Mouse Model of Alzheimer's Disease: Exploring Behavioural and Psychological Symptoms of Dementia in a …

F Kosel - 2023 - dalspace.library.dal.ca
The present work examines behavioural and psychological symptoms of dementia (BPSD)-
like behaviours in the 5xFAD mouse model of Alzheimer's disease (AD)-related amyloid …

Environmental Coordination in Health and Disease

DE Beach - 2023 - search.proquest.com
Life has evolved within a dynamic environment. In order to anticipate and prepare for
recurrent environmental changes, organisms have internalized biological solutions to …