Chemical diversity and bioactivities of monoterpene indole alkaloids (MIAs) from six Apocynaceae genera

AE Mohammed, ZH Abdul-Hameed, MO Alotaibi… - Molecules, 2021 - mdpi.com
By the end of the twentieth century, the interest in natural compounds as probable sources of
drugs has declined and was replaced by other strategies such as molecular target-based …

A Review of Rhazya stricta Decne Phytochemistry, Bioactivities, Pharmacological Activities, Toxicity, and Folkloric Medicinal Uses

A Albeshri, NA Baeshen, TA Bouback, AA Aljaddawi - Plants, 2021 - mdpi.com
The local medicinal plant Rhazya stricta Decne is reviewed for its folkloric medicinal,
phytochemical, pharmacological, biological, and toxicological features. R. stricta has been …

The current scenario of naturally occurring indole alkaloids with anticancer potential

J Song, B Zhang, M Li, J Zhang - Fitoterapia, 2023 - Elsevier
Naturally occurring indole alkaloids are ubiquitously present in nature and possess
extensive biological properties and structural diversity. Mechanistically, naturally occurring …

[HTML][HTML] Bioactivity and molecular docking of lactones isolated from Centaurea pseudosinaica Czerep

FB Alamri, TR Sobahi, HI Althagbi… - Saudi Pharmaceutical …, 2023 - Elsevier
Two cytotoxic sesquiterpene lactones, 17-epichlorohyssopifolin A (1) and chlorjanerin (2),
and a monoterpene lactone, loliolide (3) were isolated from Centaurea pseudosinaica. The …

Monoterpene Indole Alkaloids from the Aerial Parts of Rhazya stricta Induce Cytotoxicity and Apoptosis in Human Adenocarcinoma Cells

ZH Abdul-Hameed, NO Bawakid, HS Alorfi, TR Sobahi… - Molecules, 2022 - mdpi.com
Chromatographic investigation of the aerial parts of the Rhazya stricta (Apocynaceae)
resulted in the isolation of two new monoterpene indole alkaloids, 6-nor-antirhine-N1-methyl …

Investigation of Small-Molecule Constituents in Voacanga africana Seeds and Mapping of Their Spatial Distributions Using Laser Ablation Direct Analysis in Real …

AM Coon, RA Musah - ACS omega, 2023 - ACS Publications
Plant seeds are a renewable resource that can furnish access to medicinal natural products
that can only otherwise be isolated from aerial or root parts, the harvest of which may be …

The Antifungal Activities of Silver Nano-Aggregates Biosynthesized from the Aqueous Extract and the Alkaline Aqueous Fraction of Rhazya stricta against Some …

F Al-Otibi - Nanomaterials, 2023 - mdpi.com
Rhazya stricta is a major medicinal species used in indigenous medicinal herbal
medications in South Asia, the Middle East, Iran, and Iraq to treat a variety of ailments. The …

Chemical constituents of Alstonia scholaris (L.) R. Br. and their chemotaxonomic significance

Y Xu, J Liu, H Wang, X Li, Y Xia, W Ji, E Sun… - … Systematics and Ecology, 2023 - Elsevier
Phytochemical investigation on the stems of Alstonia scholaris (L.) R. Br. led to the isolation
and identification of 30 natural products, including sixteen alkaloids (1–16), nine …

Bronchodilator Secondary Metabolites from Rhazya stricta Decne Aerial Parts

MS Abdel-Kader, NU Rehman, AF Aldosari, FS Almutib… - Separations, 2022 - mdpi.com
The plant kingdom comprises medicinally useful plants that have provided many new drugs
used to treat various diseases. In our search for bronchodilator secondary metabolites from …

Antibacterial and biofilm prevention metabolites from Acanthophora spicifera

F Budiyanto, NA Albalawi, MA Ghandourah… - Open …, 2023 - degruyter.com
Acanthophora spicifera harbors a diverse array of secondary metabolites with therapeutic
potential. The aim of this study is to isolate and characterize secondary metabolites from A …