Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …

Anemia is frequent among brain-injured patients, where it has been associated with an
increased risk of poor outcome. The pathophysiology of anemia in this patient population …

Importance There is limited information about the effect of erythropoietin or a high
hemoglobin transfusion threshold after a traumatic brain injury. Objective To compare the …

Introduction The critical care management of traumatic brain injury focuses on preventing
secondary ischemic injury. Cerebral oxygen delivery is dependent upon the cerebral …

Purpose To investigate the relationship between hemoglobin (Hgb) and brain tissue oxygen
tension (PbtO 2) after severe traumatic brain injury (TBI) and to examine its impact on …

Coagulopathy in patients with traumatic brain injury is associated with an increase in
morbidity and mortality. Although timely and aggressive treatment of coagulopathy is of …

Traumatic brain injury (TBI) is a growing global problem, which is responsible for a
substantial burden of disability and death, and which generates substantial healthcare costs …

Introduction Accumulating evidence suggests that, in critically ill patients, a lower
hemoglobin transfusion threshold is safe. However, the optimal hemoglobin level and …

Currently, there is insufficient evidence to make strong recommendations regarding which
hemoglobin threshold to use as a transfusion trigger in critically-ill patients with TBI. There is …

Abstract Background The optimal hemoglobin (Hb) threshold at which to initiate red blood
cell (RBC) transfusion in patients with acute brain injury is unknown. The aim of this survey …