The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation
There is a recognized and growing need for rapid and efficient cell assays, where the size of
microfluidic devices lend themselves to the manipulation of cellular populations down to the …
microfluidic devices lend themselves to the manipulation of cellular populations down to the …
[HTML][HTML] Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics
N Shembekar, C Chaipan, R Utharala, CA Merten - Lab on a Chip, 2016 - pubs.rsc.org
Droplet-based microfluidics enables assays to be carried out at very high throughput (up to
thousands of samples per second) and enables researchers to work with very limited …
thousands of samples per second) and enables researchers to work with very limited …
Digital assays part I: partitioning statistics and digital PCR
AS Basu - SLAS TECHNOLOGY: Translating Life Sciences …, 2017 - journals.sagepub.com
A digital assay is one in which the sample is partitioned into many small containers such that
each partition contains a discrete number of biological entities (0, 1, 2, 3,…). A powerful …
each partition contains a discrete number of biological entities (0, 1, 2, 3,…). A powerful …
[HTML][HTML] Abseq: Ultrahigh-throughput single cell protein profiling with droplet microfluidic barcoding
P Shahi, SC Kim, JR Haliburton, ZJ Gartner… - Scientific reports, 2017 - nature.com
Proteins are the primary effectors of cellular function, including cellular metabolism,
structural dynamics, and information processing. However, quantitative characterization of …
structural dynamics, and information processing. However, quantitative characterization of …
Mass activated droplet sorting (mads) enables high‐throughput screening of enzymatic reactions at nanoliter scale
DA Holland‐Moritz, MK Wismer… - Angewandte Chemie …, 2020 - Wiley Online Library
Microfluidic droplet sorting enables the high‐throughput screening and selection of water‐in‐
oil microreactors at speeds and volumes unparalleled by traditional well‐plate approaches …
oil microreactors at speeds and volumes unparalleled by traditional well‐plate approaches …
[HTML][HTML] Droplet microfluidics for microbiology: techniques, applications and challenges
Droplet microfluidics has rapidly emerged as one of the key technologies opening up new
experimental possibilities in microbiology. The ability to generate, manipulate and monitor …
experimental possibilities in microbiology. The ability to generate, manipulate and monitor …
Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery
Microfluidics is an emerging and promising interdisciplinary technology which offers
powerful platforms for precise production of novel functional materials (eg, emulsion …
powerful platforms for precise production of novel functional materials (eg, emulsion …
Generation and functional assessment of 3D multicellular spheroids in droplet based microfluidics platform
Here we describe a robust, microfluidic technique to generate and analyze 3D tumor
spheroids, which resembles tumor microenvironment and can be used as a more effective …
spheroids, which resembles tumor microenvironment and can be used as a more effective …
[HTML][HTML] Using spheroids as building blocks towards 3D bioprinting of tumor microenvironment
Cancer still ranks as a leading cause of mortality worldwide. Although considerable efforts
have been dedicated to anticancer therapeutics, progress is still slow, partially due to the …
have been dedicated to anticancer therapeutics, progress is still slow, partially due to the …
Scaling up the throughput of microfluidic droplet-based materials synthesis: A review of recent progress and outlook
The last two decades have witnessed tremendous progress in the development of
microfluidic chips that generate micrometer-and nanometer-scale materials. These chips …
microfluidic chips that generate micrometer-and nanometer-scale materials. These chips …