[HTML][HTML] Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer

K Li, H Shi, B Zhang, X Ou, Q Ma, Y Chen… - … and Targeted Therapy, 2021 - nature.com
Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature
myeloid cells with immunosuppressive effects, which undergo massive expansion during …

[HTML][HTML] mRNA-based therapeutics: powerful and versatile tools to combat diseases

S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

[HTML][HTML] Myeloid-derived suppressor cells: an emerging target for anticancer immunotherapy

Y Wu, M Yi, M Niu, Q Mei, K Wu - Molecular cancer, 2022 - Springer
The clinical responses observed following treatment with immune checkpoint inhibitors
(ICIs) support immunotherapy as a potential anticancer treatment. However, a large …

[HTML][HTML] The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Tumor‐targeted drug and CpG delivery system for phototherapy and docetaxel‐enhanced immunotherapy with polarization toward M1‐type macrophages on triple …

L Chen, L Zhou, C Wang, Y Han, Y Lu, J Liu… - Advanced …, 2019 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical responses in recent years owing to
the potential of controlling metastatic disease. However, there is a limited research to prove …

[HTML][HTML] Type I interferon-mediated tumor immunity and its role in immunotherapy

R Yu, B Zhu, D Chen - Cellular and Molecular Life Sciences, 2022 - Springer
Immune checkpoint blockade (ICB) therapies have achieved remarkable clinical responses
in patients with many different types of cancer; however, most patients who receive ICB …

Compound copper chalcogenide nanocrystals

C Coughlan, M Ibanez, O Dobrozhan, A Singh… - Chemical …, 2017 - ACS Publications
This review captures the synthesis, assembly, properties, and applications of copper
chalcogenide NCs, which have achieved significant research interest in the last decade due …

Recent advances in oligonucleotide therapeutics in oncology

H Xiong, RN Veedu, SD Diermeier - International Journal of Molecular …, 2021 - mdpi.com
Cancer is one of the leading causes of death worldwide. Conventional therapies, including
surgery, radiation, and chemotherapy have achieved increased survival rates for many types …