Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis.
Lung transplantation is the only intervention shown to increase life expectancy for patients …

Lung transplantation has been established worldwide as the last treatment for end-stage
respiratory failure. However, ischemia–reperfusion injury (IRI) inevitably occurs after lung …

Calcineurin inhibitors (CNIs) revolutionized the field of organ transplantation and remain the
standard of care 40 years after the discovery of cyclosporine. The early impressive results of …

The first human lung transplantation was performed by Dr. lames Hardy at the University of
Mississippi in 1une 1963 (l). Between 1963 and 1974, 36 patients underwent lung …

We previously described a technique for en bloc double-lung transplantation that was
initially applied to select patients with cystic fibrosis and emphysema. This procedure is quite …

A shortage of suitable donors is a serious obstacle to the widespread application of isolated
lung transplantation for end-stage lung disease. We hypothesized that lung tissue likely …

Lung transplantation has become a successful method in the therapy for end-stage
pulmonary disease. While single-lung transplantation provides benefit to patients with …

Background Lung transplantation (LTx) can extend life expectancy and enhance the quality
of life for select patients with end-stage lung disease. In the setting of donor lung shortage …

Cell Death in Human Lung Transplantation: Apoptosis Inductio... : Annals of Surgery Cell Death
in Human Lung Transplantation: Apoptosis Induction in Human Lungs During Ischemia and …

Over the past 30 years, organ transplantation has been transformed from an interesting
experiment in human immunobiology to the most practical means of rehabilitating patients …