Neonatal cholestasis: emerging molecular diagnostics and potential novel therapeutics
AG Feldman, RJ Sokol - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Neonatal cholestasis is a group of rare disorders of impaired bile flow characterized by
conjugated hyperbilirubinaemia in the newborn and young infant. Neonatal cholestasis is …
conjugated hyperbilirubinaemia in the newborn and young infant. Neonatal cholestasis is …
[HTML][HTML] Alagille syndrome: diagnostic challenges and advances in management
Alagille syndrome (ALGS) is a multisystem disease characterized by cholestasis and bile
duct paucity on liver biopsy in addition to variable involvement of the heart, eyes, skeleton …
duct paucity on liver biopsy in addition to variable involvement of the heart, eyes, skeleton …
[PDF][PDF] Biliary atresia in children: update on disease mechanism, therapies, and patient outcomes
S Antala, SA Taylor - Clinics in liver disease, 2022 - Elsevier
Biliary atresia is a rare disease but remains the most common indication for pediatric liver
transplantation as there are no effective medical therapies to slow progression after …
transplantation as there are no effective medical therapies to slow progression after …
Biliary atresia as a disease starting in utero: implications for treatment, diagnosis, and pathogenesis
KR Mysore, BL Shneider… - Journal of pediatric …, 2019 - journals.lww.com
Biliary atresia (BA) is the most common reason for pediatric liver transplant. BA's varied
presentation, natural history, and treatment with the Kasai portoenterostomy have been well …
presentation, natural history, and treatment with the Kasai portoenterostomy have been well …
Neonatal cholestasis: Updates on diagnostics, therapeutics, and prevention
AG Feldman, RJ Sokol - Neoreviews, 2021 - publications.aap.org
Cholestatic jaundice is a common presenting feature of hepatobiliary and/or metabolic
dysfunction in the newborn and young infant. Timely detection of cholestasis, followed by …
dysfunction in the newborn and young infant. Timely detection of cholestasis, followed by …
Diagnostic approach to neonatal and infantile cholestasis: a position paper by the SIGENP liver disease working group
G Ranucci, C Della Corte, D Alberti… - Digestive and Liver …, 2022 - Elsevier
Neonatal and infantile cholestasis (NIC) can represent the onset of a surgically correctable
disease and of a genetic or metabolic disorder worthy of medical treatment. Timely …
disease and of a genetic or metabolic disorder worthy of medical treatment. Timely …
Diagnostic accuracy of two-dimensional shear wave elastography in detecting hepatic fibrosis in children with autoimmune hepatitis, biliary atresia and other chronic …
P Galina, E Alexopoulou, A Mentessidou, P Mirilas… - Pediatric …, 2021 - Springer
Background Although fibrosis is the main determinant of liver stiffness, other disease-related
factors usually disregarded in studies on liver elastography, such as inflammation and …
factors usually disregarded in studies on liver elastography, such as inflammation and …
Alagille syndrome: current understanding of pathogenesis, and challenges in diagnosis and management
Alagille syndrome (ALGS) is the most common inherited cholestatic liver disease
encountered by pediatric hepatologists. Unlike most other causes of cholestasis, the …
encountered by pediatric hepatologists. Unlike most other causes of cholestasis, the …
Outcomes of biliary atresia in the Nordic countries–a multicenter study of 158 patients during 2005–2016
MP Pakarinen, LS Johansen, JF Svensson… - Journal of Pediatric …, 2018 - Elsevier
Background/purpose Biliary atresia is the most common reason for newborn cholestasis and
pediatric liver transplantation. Even after normalization of serum bilirubin after …
pediatric liver transplantation. Even after normalization of serum bilirubin after …
[HTML][HTML] Recent advances in understanding biliary atresia
A Wehrman, O Waisbourd-Zinman, RG Wells - F1000Research, 2019 - ncbi.nlm.nih.gov
Biliary atresia (BA) is a neonatal liver disease characterized by progressive obstruction and
fibrosis of the extrahepatic biliary tree as well as fibrosis and inflammation of the liver …
fibrosis of the extrahepatic biliary tree as well as fibrosis and inflammation of the liver …